Publikationen Institut für Biologische Chemie (gegr. 2011)
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Heuer J, Heuer F, Stuermer R, Harder S, Schlueter H, Emidio NB et al. The Tumor Suppressor TFF1 Occurs in Different Forms and Interacts with Multiple Partners in the Human Gastric Mucus Barrier: Indications for Diverse Protective Functions. International Journal of Molecular Sciences. 2020 Apr;21(7):2508. doi: 10.3390/ijms21072508
Toprakcioglu Z, Hakala TA, Levin A, Becker CFW, Bernandes GGL, Knowles TPJ. Multi-scale microporous silica microcapsules from gas-in water-in oil emulsions. Soft Matter. 2020 Mär 28;16(12):3082-3087. doi: 10.1039/c9sm02274k
Schilling PE, Kontaxis G, Dragosits M, Schiestl RH, Becker CFW, Maier I. Mannosylated hemagglutinin peptides bind cyanovirin-N independent of disulfide-bonds in complementary binding sites. RSC Advances . 2020 Mär 19;10(19):11079-11087. doi: 10.1039/d0ra01128b
Kalra J, Mangali S, Bhat A, Jadhav K, Dhar A. Selective inhibition of PKR improves vascular inflammation and remodelling in high fructose treated primary vascular smooth muscle cells. Biochimica et Biophysica Acta - Molecular Basis of Disease. 2020 Mär 1;1866(3):165606. doi: 10.1016/j.bbadis.2019.165606
Olsen GL, Szekely O, Mateos B, Kaderavek P, Ferrage F, Konrat R et al. Sensitivity-enhanced three-dimensional and carbon-detected two-dimensional NMR of proteins using hyperpolarized water. Journal of Biomolecular NMR. 2020 Mär;74(2-3):161-171. doi: 10.1007/s10858-020-00301-5
Novakovic M, Olsen GL, Pinter G, Hymon D, Fuertig B, Schwalbe H et al. A 300-fold enhancement of imino nucleic acid resonances by hyperpolarized water provides a new window for probing RNA refolding by 1D and 2D NMR. Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2020 Feb 4;117(5):2449-2455. doi: 10.1073/pnas.1916956117
Mukherjee S, Matveenko M, Becker CFW. Impact of site-specific non-enzymatic posttranslational modification on the structure-activity attributes of human Heat Shock Protein 27 (Hsp27). 2020. Beitrag in 4th Chemical Ligation Meeting, Orléans, Frankreich.
Jadhav KB, Woolcock KJ, Muttenthaler M. Anhydrous hydrogen fluoride cleavage in boc solid phase peptide synthesis. in Hussein WM, Skwarczynski M, Toth I, Hrsg., Peptide Synthesis: Methods and Protocols. Band 2103. Humana Press, Springer. 2020. S. 41-57. (Methods in Molecular Biology). doi: 10.1007/978-1-0716-0227-0_4
Mukherjee S, Matveenko M, Becker CFW. Highly Precise Protein Semisynthesis through Ligation–Desulfurization Chemistry in Combination with Phenacyl Protection of Native Cysteines. in Vila-Perelló M, Hrsg., Expressed Protein Ligation: Methods and Protocols. Band 2133. Humana Press, Inc. 2020. S. 343-358. (Methods in Molecular Biology, Band 2133). doi: 10.1007/978-1-0716-0434-2_17
Groß K, Kurzbach D, Angele CM. NMR for food profiling – Long Drink, Short Experiment: Ein interdisziplinärer Zugang zur Förderung von Urteilskompetenz. Haushalt in Bildung und Forschung. 2020;9(4):79-96. doi: 10.3224/hibifo.v9i4.06
Muttenthaler M, Nevin ST, Inserra M, Lewis RJ, Adams DJ, Alewood PF. On-Resin Strategy to Label α-Conotoxins: Cy5-RgIA, a Potent α9α10 Nicotinic Acetylcholine Receptor Imaging Probe. Australian Journal of Chemistry. 2020;73(4):327-333. doi: 10.1071/CH19456
Conibear AC, Schmid A, Kamalov M, Becker CFW, Bello C. Recent Advances in Peptide-Based Approaches for Cancer Treatment. Current Medicinal Chemistry. 2020;27(8):1174-1205. doi: 10.2174/0929867325666171123204851
Dürrauer L, Muratspahic E, Gattringer J, Keov P, Mendel HC, Pfleger KDG et al. I8-arachnotocin-an arthropod- derived G protein-biased ligand of the human vasopressin V-2 receptor. Scientific Reports. 2019 Dez 17;9(1):19295. doi: 10.1038/s41598-019-55675-w
Jin A-H, Muttenthaler M, Dutertre S, Himaya SWA, Kaas Q, Craik DJ et al. Conotoxins: Chemistry and Biology. Chemical Reviews. 2019 Nov 13;119(21):11510-11549. doi: 10.1021/acs.chemrev.9b00207
Conibear AC, Rosengren KJ, Becker CFW, Kaehlig H. Random coil shifts of posttranslationally modified amino acids. Journal of Biomolecular NMR. 2019 Nov;73(10-11):587-599. doi: 10.1007/s10858-019-00270-4
Hackl S, Becker CFW. Prion protein-Semisynthetic prion protein (PrP) variants with posttranslational modifications. Journal of Peptide Science. 2019 Okt;25(10):e3216. doi: 10.1002/psc.3216
Schlatzer T, Kriegesmann J, Schroeder H, Trobe M, Lembacher-Fadum C, Santner S et al. Labeling and Natural Post-Translational Modification of Peptides and Proteins via Chemoselective Pd-Catalyzed Prenylation of Cysteine. Journal of the American Chemical Society. 2019 Sep 18;141(37):14931-14937. doi: 10.1021/jacs.9b08279
Del Favero G, Bialas F, Grabher-Wusche S, Wittig A, Bräuer B, Gerthsen D et al. Silica particles with a quercetin-R5 peptide conjugate are taken up into HT-29 cells and translocate into the nucleus. Chemical Communications. 2019 Aug 21;55(65):9649-9652. doi: 10.1039/c9cc02215e
Sadet A, Stavarache C, Bacalum M, Radu M, Bodenhausen G, Kurzbach D et al. Hyperpolarized Water Enhances Two-Dimensional Proton NMR Correlations: A New Approach for Molecular Interactions. Journal of the American Chemical Society. 2019 Aug 14;141(32):12448-12452. doi: 10.1021/jacs.9b03651
Jannin S, Dumez J-N, Giraudeau P, Kurzbach D. Application and methodology of dissolution dynamic nuclear polarization in physical, chemical and biological contexts. Journal of Magnetic Resonance. 2019 Aug;305:41-50. doi: 10.1016/j.jmr.2019.06.001
Kiryutin AS, Rodin BA, Yurkovskaya AV, Ivanov KL, Kurzbach D, Jannin S et al. Transport of hyperpolarized samples in dissolution-DNP experiments. Physical Chemistry Chemical Physics. 2019 Jul 7;21(25):13696-13705. doi: 10.1039/c9cp02600b
Sicoli G, Vezin H, Ledolter K, Kress T, Kurzbach D. Conformational tuning of a DNA-bound transcription factor. Nucleic Acids Research. 2019 Jun 4;47(10):5429-5435. doi: 10.1093/nar/gkz291
Poetgens AJG, Conibear AC, Altdorf C, Hilzendeger C, Becker CFW. Tumor-Targeting Immune System Engagers (ISErs) Activate Human Neutrophils after Binding to Cancer Cells. Biochemistry. 2019 Jun 4;58(22):2642-2652. doi: 10.1021/acs.biochem.9b00169
Emidio NB, Hoffmann W, Brierley SM, Muttenthaler M. Trefoil Factor Family: Unresolved Questions and Clinical Perspectives. Trends in Biochemical Sciences. 2019 Mai;44(5):387-390. doi: 10.1016/j.tibs.2019.01.004
Kress T, Walrant A, Bodenhausen G, Kurzbach D. Long-Lived States in Hyperpolarized Deuterated Methyl Groups Reveal Weak Binding of Small Molecules to Proteins. Journal of Physical Chemistry Letters. 2019 Apr 4;10(7):1523-1529. doi: 10.1021/acs.jpclett.9b00149
Conibear AC, Thewes K, Groysbeck N, Becker CFW. Multifunctional Scaffolds for Assembling Cancer-Targeting Immune Stimulators Using Chemoselective Ligations. Frontiers in Chemistry. 2019 Mär 6;7:113. doi: 10.3389/fchem.2019.00113
Kamalov M, Kaehlig H, Rentenberger C, Müllner A, Peterlik H, Becker CFW. Ovalbumin Epitope SIINFEKL Self-Assembles into a Supramolecular Hydrogel. Scientific Reports. 2019 Feb 25;9(1):2696. doi: 10.1038/s41598-019-39148-8
Ellmer D, Brehs M, Haj-Yahya M, Lashuel HA, Becker CFW. Single Posttranslational Modifications in the Central Repeat Domains of Tau4 Impact its Aggregation and Tubulin Binding. Angewandte Chemie (International Edition). 2019 Feb 4;58(6):1616-1620. doi: 10.1002/anie.201805238
Conibear AC, Watson EE, Payne RJ, Becker CFW. Native chemical ligation in protein synthesis and semi-synthesis. Chemical Society Reviews. 2018 Dez 21;47(24):9046-9068. doi: 10.1039/c8cs00573g
Liutkeviciute Z, Gil-Mansilla E, Eder T, Casillas-Perez B, Di Giglio MG, Muratspahic E et al. Oxytocin-like signaling in ants influences metabolic gene expression and locomotor activity. The FASEB Journal. 2018 Dez;32(12):6808-6821. doi: 10.1096/fj.201800443
Kamalov M, Capel PD, Rentenberger C, Müllner A, Peterlik H, Becker CFW. Silaffin-Inspired Peptide Assemblies Template Silica Particles with Variable Morphologies. Chemnanomat. 2018 Dez;4(12):1209-1213. doi: 10.1002/cnma.201800340
Pfaff S, Nehring T, Pichler V, Cardinale J, Mitterhauser M, Hacker M et al. Development and evaluation of a rapid analysis for HEPES determination in
68Ga-radiotracers. EJNMMI Research. 2018 Okt 23;8(1):95. doi: 10.1186/s13550-018-0449-6, 10.1186/s13550-018-0449-6
Herzig V, de Araujo AD, Greenwood KP, Chin YKY, Windley MJ, Chong Y et al. Evaluation of chemical strategies for improving the stability and oral toxicity of insecticidal peptides. Biomedicines. 2018 Sep 1;6(3):90. doi: 10.3390/biomedicines6030090
Mukherjee S, Matveenko M, Becker CFW. Accessing semisynthetic Hsp27 carrying site-specific non-enzymatic post-translational modification implicated in disease. Journal of Peptide Science. 2018 Sep;24:S98-S99.
Kriegesmann J, Schlatzer T, Breinbauer R, Becker CFW. Pd-catalyzed cysteine modification of peptides and proteins. Journal of Peptide Science. 2018 Sep;24:S98-S98.
Schrems M, Becker CFW, Bello C. Synthesis of a new generation auxiliary for cysteine-independent native chemical ligation and chemoenzymatic modification. Journal of Peptide Science. 2018 Sep;24:S99-S99.
Schmid A, Bello C, Becker CFW. Synthesis of Homogeneously Glycosylated Soluble Fas Ligand Variants. Journal of Peptide Science. 2018 Sep;24:S98-S98.
Conibear AC, Poetgens AJG, Brehs M, Altdorf C, Hilzendeger C, Steitz J et al. Synthetic integrin-binding immune stimulators target cancer cells and prevent tumor formation. Journal of Peptide Science. 2018 Sep;24:S67-S67.
Bello C, Papini AM, Becker CFW. Toward homogeneous glycoproteins via auxiliary-assisted sequential glycosylation and ligation of peptides. Journal of Peptide Science. 2018 Sep;24:S50-S50.
Feichtinger M, Sara T, Platzer G, Mateos B, Bokhovchuk F, Chène P et al. 1H, 13C, 15N resonance assignment of human YAP 50–171 fragment. Biomolecular NMR Assignments. 2018 Apr;12(1):179-182. doi: 10.1007/s12104-018-9805-8
Conibear AC, Muttenthaler M. Advancing the Frontiers of Chemical Protein Synthesis-The 7th CPS Meeting, Haifa, Israel. Cell Chemical Biology. 2018 Mär 15;25(3):247-254. doi: 10.1016/j.chembiol.2018.03.001
Conibear AC, Poetgens AJG, Thewes K, Altdorf C, Hilzendeger C, Becker CFW. Synthetic Cancer-Targeting Innate Immune Stimulators Give Insights into Avidity Effects. ChemBioChem: a european journal of chemical biology. 2018 Mär 2;19(5):459-469. doi: 10.1002/cbic.201700522
Hufnagel B, Silberbauer K, Löppert R, Viernstein H, Praznik W, Müller M. Fermentation of non-digestible raffinose family oligosaccharides and galactomannans by probiotics. Trends in Food Science & Technology. 2018 Mär;9(3):1638-1646. doi: 10.1039/c7fo01887h
Kamalov M, Hajradini A, Rentenberger C, Becker CFW. N-terminal residues of silaffin peptides impact morphology of biomimetic silica particles. Materials Letters. 2018 Feb 1;212:114-117. doi: 10.1016/j.matlet.2017.10.050
Arrowsmith S, Keov P, Muttenthaler M, Gruber CW. Contractility Measurements of Human Uterine Smooth Muscle to Aid Drug Development. Journal of Visualized Experiments. 2018 Jan;2018(131):e56639. doi: 10.3791/56639
Matveenko M, Hackl S, Becker CFW. Utility of the Phenacyl Protecting Group in Traceless Protein Semisynthesis through Ligation-Desulfurization Chemistry. ChemistryOpen. 2018 Jan;7(1):106-110. doi: 10.1002/open.201700180
Brehs M, Poetgens AJG, Steitz J, Thewes K, Schwarz J, Conibear AC et al. Synthetic integrin-binding immune stimulators target cancer cells and prevent tumor formation. Scientific Reports. 2017 Dez 14;7:17592. doi: 10.1038/s41598-017-17627-0
Muttenthaler M, Andersson A, Vetter I, Menon R, Busnelli M, Ragnarsson L et al. Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species. Science Signaling. 2017 Dez 5;10(508):eaan3398. doi: 10.1126/scisignal.aan3398
Gell AL, Groysbeck N, Becker CFW, Conibear AC. A comparative study of synthetic and semisynthetic approaches for ligating the epidermal growth factor to a bivalent scaffold. Journal of Peptide Science. 2017 Dez;23(12):871-879. doi: 10.1002/psc.3051
Conibear A, Pötgens A, Keßler C, Hilzendeger C, Thewes K, Becker CFW. Exploring avidity effects using synthetic cancer-targeted immune stimulators. in Conference Proceedings. 2017
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