Publikationen

Schlatzer T, Kriegesmann J, Schroeder H, Trobe M, Lembacher-Fadum C, Santner S et al. Labeling and Natural Post-Translational Modification of Peptides and Proteins via Chemoselective Pd-Catalyzed Prenylation of Cysteine. Journal of the American Chemical Society. 2019 Sep 18;141(37):14931-14937. doi: 10.1021/jacs.9b08279

Del Favero G, Bialas F, Grabher-Wusche S, Wittig A, Bräuer B, Gerthsen D et al. Silica particles with a quercetin-R5 peptide conjugate are taken up into HT-29 cells and translocate into the nucleus. Chemical Communications. 2019 Aug 21;55(65):9649-9652. doi: 10.1039/c9cc02215e

Sadet A, Stavarache C, Bacalum M, Radu M, Bodenhausen G, Kurzbach D et al. Hyperpolarized Water Enhances Two-Dimensional Proton NMR Correlations: A New Approach for Molecular Interactions. Journal of the American Chemical Society. 2019 Aug 14;141(32):12448-12452. doi: 10.1021/jacs.9b03651

Jannin S, Dumez JN, Giraudeau P, Kurzbach D. Application and methodology of dissolution dynamic nuclear polarization in physical, chemical and biological contexts. Journal of Magnetic Resonance. 2019 Aug;305:41-50. doi: 10.1016/j.jmr.2019.06.001

Kiryutin AS, Rodin BA, Yurkovskaya AV, Ivanov KL, Kurzbach D, Jannin S et al. Transport of hyperpolarized samples in dissolution-DNP experiments. Physical Chemistry Chemical Physics. 2019 Jul 7;21(25):13696-13705. doi: 10.1039/c9cp02600b

Sicoli G, Vezin H, Ledolter K, Kress T, Kurzbach D. Conformational tuning of a DNA-bound transcription factor. Nucleic Acids Research. 2019 Jun 4;47(10):5429-5435. doi: 10.1093/nar/gkz291

Poetgens AJG, Conibear AC, Altdorf C, Hilzendeger C, Becker CFW. Tumor-Targeting Immune System Engagers (ISErs) Activate Human Neutrophils after Binding to Cancer Cells. Biochemistry. 2019 Jun 4;58(22):2642-2652. doi: 10.1021/acs.biochem.9b00169

Emidio NB, Hoffmann W, Brierley SM, Muttenthaler M. Trefoil Factor Family: Unresolved Questions and Clinical Perspectives. Trends in Biochemical Sciences. 2019 Mai;44(5):387-390. doi: 10.1016/j.tibs.2019.01.004

Kress T, Walrant A, Bodenhausen G, Kurzbach D. Long-Lived States in Hyperpolarized Deuterated Methyl Groups Reveal Weak Binding of Small Molecules to Proteins. Journal of Physical Chemistry Letters. 2019 Apr 4;10(7):1523-1529. doi: 10.1021/acs.jpclett.9b00149

Conibear AC, Thewes K, Groysbeck N, Becker CFW. Multifunctional Scaffolds for Assembling Cancer-Targeting Immune Stimulators Using Chemoselective Ligations. Frontiers in Chemistry. 2019 Mär 6;7:113. doi: 10.3389/fchem.2019.00113

Kamalov M, Kaehlig H , Rentenberger C, Müllner A, Peterlik H , Becker CFW. Ovalbumin Epitope SIINFEKL Self-Assembles into a Supramolecular Hydrogel. Scientific Reports. 2019 Feb 25;9(1):2696. doi: 10.1038/s41598-019-39148-8

Ellmer D, Brehs M, Haj-Yahya M, Lashuel HA, Becker CFW. Single Posttranslational Modifications in the Central Repeat Domains of Tau4 Impact its Aggregation and Tubulin Binding. Angewandte Chemie (International Edition). 2019 Feb 4;58(6):1616-1620. doi: 10.1002/anie.201805238

Conibear AC, Watson EE, Payne RJ, Becker CFW. Native chemical ligation in protein synthesis and semi-synthesis. Chemical Society Reviews. 2018 Dez 21;47(24):9046-9068. doi: 10.1039/c8cs00573g

Liutkeviciute Z, Gil-Mansilla E, Eder T, Casillas-Perez B, Di Giglio MG, Muratspahic E et al. Oxytocin-like signaling in ants influences metabolic gene expression and locomotor activity. The FASEB Journal. 2018 Dez;32(12):6808-6821. doi: 10.1096/fj.201800443

Kamalov M, Capel PD, Rentenberger C, Müllner A, Peterlik H , Becker CFW. Silaffin-Inspired Peptide Assemblies Template Silica Particles with Variable Morphologies. Chemnanomat. 2018 Dez;4(12):1209-1213. doi: 10.1002/cnma.201800340

Pfaff S, Nehring T, Pichler V, Cardinale J, Mitterhauser M, Hacker M et al. Development and evaluation of a rapid analysis for HEPES determination in ⁶⁸Ga-radiotracers. EJNMMI Research. 2018 Okt 23;8(1):95. doi: 10.1186/s13550-018-0449-6, 10.1186/s13550-018-0449-6

Herzig V, de Araujo AD, Greenwood KP, Chin YKY, Windley MJ, Chong Y et al. Evaluation of chemical strategies for improving the stability and oral toxicity of insecticidal peptides. Biomedicines. 2018 Sep 1;6(3):90. doi: 10.3390/biomedicines6030090

Mukherjee S, Matveenko M, Becker CFW. Accessing semisynthetic Hsp27 carrying site-specific non-enzymatic post-translational modification implicated in disease. Journal of Peptide Science. 2018 Sep;24:S98-S99.

Kriegesmann J, Schlatzer T, Breinbauer R, Becker CFW. Pd-catalyzed cysteine modification of peptides and proteins. Journal of Peptide Science. 2018 Sep;24:S98-S98.

Schrems M, Becker CFW, Bello C. Synthesis of a new generation auxiliary for cysteine-independent native chemical ligation and chemoenzymatic modification. Journal of Peptide Science. 2018 Sep;24:S99-S99.

Schmid A, Bello C, Becker CFW. Synthesis of Homogeneously Glycosylated Soluble Fas Ligand Variants. Journal of Peptide Science. 2018 Sep;24:S98-S98.

Conibear AC, Poetgens AJG, Brehs M, Altdorf C, Hilzendeger C, Steitz J et al. Synthetic integrin-binding immune stimulators target cancer cells and prevent tumor formation. Journal of Peptide Science. 2018 Sep;24:S67-S67.

Bello C, Papini AM, Becker CFW. Toward homogeneous glycoproteins via auxiliary-assisted sequential glycosylation and ligation of peptides. Journal of Peptide Science. 2018 Sep;24:S50-S50.

Feichtinger M, Sara T, Platzer G, Mateos B, Bokhovchuk F, Chène P et al. 1H, 13C, 15N resonance assignment of human YAP 50–171 fragment. Biomolecular NMR Assignments. 2018 Apr;12(1):179-182. doi: 10.1007/s12104-018-9805-8

Conibear AC, Muttenthaler M. Advancing the Frontiers of Chemical Protein Synthesis-The 7th CPS Meeting, Haifa, Israel. Cell Chemical Biology. 2018 Mär 15;25(3):247-254. doi: 10.1016/j.chembiol.2018.03.001

Conibear AC, Poetgens AJG, Thewes K, Altdorf C, Hilzendeger C, Becker CFW. Synthetic Cancer-Targeting Innate Immune Stimulators Give Insights into Avidity Effects. ChemBioChem: a european journal of chemical biology. 2018 Mär 2;19(5):459-469. doi: 10.1002/cbic.201700522

Hufnagel B, Silberbauer K, Löppert R, Viernstein H, Praznik W, Müller M. Fermentation of non-digestible raffinose family oligosaccharides and galactomannans by probiotics. Trends in Food Science & Technology. 2018 Mär;9(3):1638-1646. doi: 10.1039/c7fo01887h

Kamalov M, Hajradini A, Rentenberger C , Becker CFW. N-terminal residues of silaffin peptides impact morphology of biomimetic silica particles. Materials Letters. 2018 Feb 1;212:114-117. doi: 10.1016/j.matlet.2017.10.050

Arrowsmith S, Keov P, Muttenthaler M, Gruber CW. Contractility Measurements of Human Uterine Smooth Muscle to Aid Drug Development. Journal of Visualized Experiments. 2018 Jan;2018(131):e56639. doi: 10.3791/56639

Matveenko M, Hackl S, Becker CFW. Utility of the Phenacyl Protecting Group in Traceless Protein Semisynthesis through Ligation-Desulfurization Chemistry. ChemistryOpen. 2018 Jan;7(1):106-110. doi: 10.1002/open.201700180

Brehs M, Poetgens AJG, Steitz J, Thewes K, Schwarz J, Conibear AC et al. Synthetic integrin-binding immune stimulators target cancer cells and prevent tumor formation. Scientific Reports. 2017 Dez 14;7:17592. doi: 10.1038/s41598-017-17627-0

Muttenthaler M, Andersson A, Vetter I, Menon R, Busnelli M, Ragnarsson L et al. Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species. Science Signaling. 2017 Dez 5;10(508):eaan3398. doi: 10.1126/scisignal.aan3398

Gell AL, Groysbeck N, Becker CFW, Conibear AC. A comparative study of synthetic and semisynthetic approaches for ligating the epidermal growth factor to a bivalent scaffold. Journal of Peptide Science. 2017 Dez;23(12):871-879. doi: 10.1002/psc.3051

Conibear A, Pötgens A, Keßler C, Hilzendeger C, Thewes K, Becker CFW. Exploring avidity effects using synthetic cancer-targeted immune stimulators. in Conference Proceedings. 2017

Muttenthaler M. Multivalent Ligand Design – Chemistry and Applications. in Conference Proceedings. 2017

Hellinger R, Thell K, Vasileva M, Muhammad T, Gunasekera S, Kuemmel D et al. Chemical Proteomics for Target Discovery of Head-to-Tail Cyclized Mini-Proteins. Frontiers in Chemistry. 2017 Okt 11;5:73. doi: 10.3389/fchem.2017.00073

Pasalic D, Weber B, Giannone C, Anelli T, Mller R, Fagioli C et al. A peptide extension dictates IgM assembly. Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2017 Okt 10;114(41):E8575-E8584. doi: 10.1073/pnas.1701797114

Conibear AC, Hager S, Mayr J, Klose MHM, Keppler BK , Kowol CR et al. Multifunctional α _vβ ₆ Integrin-Specific Peptide-Pt(IV) Conjugates for Cancer Cell Targeting. Bioconjugate Chemistry. 2017 Sep 20;28(9):2429-2439. doi: 10.1021/acs.bioconjchem.7b00421

Bello C, Becker CFW. A dual functional peptide-auxiliary conjugate for C-to-N and N-to-C sequential native chemical ligation of glycopeptides. Bioorganic & Medicinal Chemistry. 2017 Sep 15;25(18):5016-5021. doi: 10.1016/j.bmc.2017.05.046

Becker CFW. Peptide & protein ligation. Bioorganic & Medicinal Chemistry. 2017 Sep 15;25(18):4925-4925. doi: 10.1016/j.bmc.2017.08.041

Matveenko M, Becker CFW. Synthetic Approach to Argpyrimidine as a Tool for Investigating Nonenzymatic Posttranslational Modification of Proteins. Synlett: accounts and rapid communications in synthetic organic chemistry. 2017 Sep;28(15):1950-1955. doi: 10.1055/s-0036-1588225

Araman C, Thompson RE, Wang S, Hackl S, Payne RJ, Becker CFW. Semisynthetic prion protein (PrP) variants carrying glycan mimics at position 181 and 197 do not form fibrils. Chemical Science. 2017 Jul 24;8(9):6626-6632. doi: 10.1039/c7sc02719b

Kaur H, Kamalov M, Brimble MA. Chemical Synthesis of Peptides Containing Site-Specific Advanced Glycation Endproducts. Accounts of Chemical Research. 2016 Okt 18;49(10):2199-2208. doi: 10.1021/acs.accounts.6b00366

Schwaighofer A, Alcaraz MR, Araman MC, Goicoechea H, Lendl B. External cavity-quantum cascade laser infrared spectroscopy for secondary structure analysis of proteins at low concentrations. Scientific Reports. 2016 Sep 16;6:33556. doi: 10.1038/srep33556

Matveenko M, Cichero E, Fossa P, Becker CFW. Impaired Chaperone Activity of Human Heat Shock Protein Hsp27 Site-Specifically Modified with Argpyrimidine. Angewandte Chemie (International Edition). 2016 Sep 12;55(38):11397-11402. doi: 10.1002/anie.201605366

Conibear A, Farbiarz K, Becker CFW. Chemoselective ligations to increase the modularity of synthetic antibody-like molecules for cancer therapy. 2016. Beitrag in INDICAR - Workshop 2016, Palermo, Italien.

Araman MC, Becker CFW. Semisynthesis and characterization of homogeneously PEGylated full length Prion Protein (PrP) derivatives. in Conference Proceedings. 2016

Ellmer D, Brehs M, Becker CFW. Semisynthetic Tau-4 Variants with site-selective Modifications in the Central Repeat Region. in Conference Proceedings. 2016

Bello C, Gavin AC, Becker CFW. AN AUXILIARY-BASED APPROACH FOR THE SEQUENTIAL HOMOGENEOUS GLYCOSYLATION AND LIGATION OF PEPTIDES. Journal of Peptide Science. 2016 Sep;22(S2):S88-S88. doi: 10.1002/psc.2950

Conibear AC, Farbiarz K, Becker CFW. CHEMOSELECTIVE LIGATIONS TO INCREASE THE MODULARITY OF SYNTHETIC ANTIBODY-LIKE MOLECULES FOR CANCER THERAPY. Journal of Peptide Science. 2016 Sep;22(S2):S18-S18.

Publikationen Institut für Biologische Chemie (gegr. 2011)