Publikationen

Turhan E, Minaei M, Narwal P, Meier B, Kouřil K, Kurzbach D. Short-lived calcium carbonate precursors observed in situ via Bullet-dynamic nuclear polarization. Communications Chemistry. 2024 Dez;7(1):210. doi: 10.1038/s42004-024-01300-5

Turhan E, Goldberga I, Pötzl C, Keil W, Guigner JM, Haßler MFT et al. Branched Polymeric Prenucleation Assemblies Initiate Calcium Phosphate Precipitation. Journal of the American Chemical Society. 2024 Sep 18;146(37):25614-25624. Epub 2024. doi: 10.1021/jacs.4c07325

Jandl B, Dighe S, Gasche C, Makristathis A, Muttenthaler M. Intestinal biofilms: pathophysiological relevance, host defense, and therapeutic opportunities. Clinical microbiology reviews. 2024 Sep 12;37(3):e0013323. Epub 2024 Jul 12. doi: 10.1128/cmr.00133-23

Jandl B, Zheng R, Muttenthaler M, Baell J. Novel Diacyl-hydrazide Compounds as Potential Therapeutics for Visceral Leishmaniasis. ACS Omega. 2024 Sep 3;9(35):37170-37182. Epub 2024 Aug 22. doi: 10.1021/acsomega.4c04517

Muttenthaler M. CHEMICAL STRATEGIES TO TUNE POTENCY, SELECTIVITY AND STABILITY OF VENOM PEPTIDES. Toxicon. 2024 Sep;248:108028.

Kozak F, Brandis D , Pötzl C, Epasto LM, Reichinger D, Obrist D et al. An Atomistic View on the Mechanism of Diatom Peptide-Guided Biomimetic Silica Formation. Advanced science. 2024 Aug 14;11(30):2401239. Epub 2024. doi: 10.1002/advs.202401239

Zachrdla M , Turhan E , Pötzl C, Sadet A, Vasos PR, Kurzbach D. Hyperpolarized nuclear Overhauser enhancement of alanine methyl groups by doubly relayed proton exchange. Journal of Magnetic Resonance. 2024 Jul;364:107727. doi: 10.1016/j.jmr.2024.107727

Epasto LM, Maimbourg T, Rosso A, Kurzbach D. Unified understanding of the breakdown of thermal mixing dynamic nuclear polarization: The role of temperature and radical concentration. Journal of Magnetic Resonance. 2024 Mai;362:107670. doi: 10.1016/j.jmr.2024.107670

Schmid A, Bello C, Becker CFW. Synthesis of N-Glycosylated Soluble Fas Ligand. Chemistry - A European Journal. 2024 Apr 25;30(24):e202400120. Epub 2024 Feb 16. doi: 10.1002/chem.202400120

Perisic M, Woolcock K, Hering A, Mendel H, Muttenthaler M. Oxytocin and vasopressin signaling in health and disease. Trends in Biochemical Sciences. 2024 Apr;49(4):361-377. doi: 10.1016/j.tibs.2024.01.010

Mengrelis K, Niederacher G, Prickler L, Kainz V, Weijler AM, Rudolph E et al. Coupling of a Major Allergen to the Surface of Immune Cells for Use in Prophylactic Cell Therapy for the Prevention of IgE-Mediated Allergy. Cells. 2024 Mär;13(5):446. doi: 10.3390/cells13050446

Vogl DP, Mateos B, Migotti M , Felkl M, Conibear AC, Konrat R et al. Semisynthesis of segmentally isotope-labeled and site-specifically palmitoylated CD44 cytoplasmic tail. Bioorganic and Medicinal Chemistry. 2024 Feb 15;100:117617. doi: 10.1016/j.bmc.2024.117617

Kalaba P, Sanchez de la Rosa C, Möller A, Alewood PF, Muttenthaler M. Targeting the Oxytocin Receptor for Breast Cancer Management: A Niche for Peptide Tracers. Journal of Medicinal Chemistry. 2024 Feb 8;67(3):1625-1640. doi: 10.1021/acs.jmedchem.3c01089

Epasto LM, Pötzl C , Peterlik H, Khalil M, Saint-Pierre C, Gasparutto D et al. NMR-identification of the interaction between BRCA1 and the intrinsically disordered monomer of the Myc-associated factor X. Protein Science. 2024 Jan;33(1):e4849. doi: 10.1002/pro.4849

Orgler E, Baumgartner M, Duller S, Kumptisch C, Hausmann B, Moser D et al. Archaea influence composition of endoscopically visible ileocolonic biofilms. Gut microbes. 2024;16(1):2359500. doi: 10.1080/19490976.2024.2359500

Savchenko V, Jaegers M, Rasche R, Herrmann E, König S, Kümmel D et al. Unraveling key steps in the biosynthesis of antimicrobial methylated unsaturated 2-alkyl-4-quinolones of Burkholderia thailandensis. Cell Reports Physical Science. 2024;5(8):102100. doi: 10.1016/j.xcrp.2024.102100

Savchenko V, Szamosvári D , Bao Y , Pignitter M , Böttcher T. Biosynthetic flexibility of Pseudomonas aeruginosa leads to hydroxylated 2-alkylquinolones with proinflammatory host response. Communications Chemistry. 2023 Dez;6(1):138. doi: 10.1038/s42004-023-00937-y

Dunajova Z, Mateu BP, Radler P, Lim K, Brandis D, Velicky P et al. Chiral and nematic phases of flexible active filaments. Nature Physics. 2023 Dez;19(12):1916-1926. doi: 10.1038/s41567-023-02218-w

Spreitzer I, Keife J, Strasser T, Kalaba P, Lubec J, Neuhaus W et al. Pharmacokinetics of Novel Dopamine Transporter Inhibitor CE-123 and Modafinil with a Focus on Central Nervous System Distribution. International Journal of Molecular Sciences. 2023 Dez;24(23):16956. doi: 10.3390/ijms242316956

Muratspahić E, Deibler K, Han J, Tomašević N, Jadhav KB, Olivé-Marti AL et al. Design and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptor. Nature Communications. 2023 Nov 28;14(1):8064. doi: 10.1038/s41467-023-43718-w

Wirth U, Raabe K, Kalaba P, Keimpema E, Muttenthaler M, König B. Photoswitchable Probes of Oxytocin and Vasopressin. Journal of Medicinal Chemistry. 2023 Nov 9;66(21):14853-14865. doi: 10.1021/acs.jmedchem.3c01415

Schwarz P, Jadhav KB, Gruber C, Hellinger R. Blood Brain Barrier - Peptide Shuttles For Drug Delivery Into The CNS. British Journal of Pharmacology. 2023 Okt 11;180(Supplement1):525-526. Meeting Abstract: P0666.

Perisic M, Kalaba P, Keimpema E, Muttenthaler M, Gruber C. Development and application of fluorescent oxytocin receptor tracers. British Journal of Pharmacology. 2023 Okt 11;180(Supplement1):694-694. Meeting Abstract: P0984.

Turhan E , Pötzl C, Keil W, Negroni M, Kouřil K, Meier B et al. Biphasic NMR of Hyperpolarized Suspensions-Real-Time Monitoring of Solute-to-Solid Conversion to Watch Materials Grow. The Journal of Physical Chemistry Part C (Nanomaterials and Interfaces). 2023 Okt 5;127(39):19591-19598. doi: 10.1021/acs.jpcc.3c04198

Ückert AK, Rütschlin S, Gutbier S, Wörz NC, Miah MR, Martins AC et al. Identification of the bacterial metabolite aerugine as potential trigger of human dopaminergic neurodegeneration. Environment International. 2023 Okt 3;180:108229. doi: 10.1016/j.envint.2023.108229

Kalaba P, Pacher K, Neill PJ, Dragacevic V, Zehl M , Wackerlig J et al. Chirality Matters: Fine-Tuning of Novel Monoamine Reuptake Inhibitors Selectivity through Manipulation of Stereochemistry. Biomolecules. 2023 Sep;13(9):1415. doi: 10.3390/biom13091415

Schrems M, Kravchuk A , Niederacher G , Exler F, Bello C, Becker CFW. Light-Cleavable Auxiliary for Diselenide–Selenoester Ligations of Peptides and Proteins. Chemistry - A European Journal. 2023 Aug 15;29(46):e202301253. doi: 10.1002/chem.202301253

Kriegesmann J, Schlatzer T, Che K, Altdorf C, Huhmann S, Kählig H et al. Constraining and Modifying Peptides Using Pd-Mediated Cysteine Allylation. ChemBioChem. 2023 Jul 3;24(13):e202300098. doi: 10.1002/cbic.202300098

Mukherjee S, Vogl DP, Becker CFW. Site-Specific Glycation of Human Heat Shock Protein (Hsp27) Enhances Its Chaperone Activity. ACS Chemical Biology. 2023 Jul;18(8):1760-1771. doi: 10.1021/acschembio.3c00214

Bello C, Pranzini E, Piemontese E, Schrems M, Taddei ML, Giovannelli L et al. Chemoenzymatic Synthesis of Glycopeptides to Explore the Role of Mucin 1 Glycosylation in Cell Adhesion. ChemBioChem. 2023 Jun 15;24(12):e202200741. doi: 10.1002/cbic.202200741

Szamosvari D, Savchenko V, Badouin N, Böttcher T. Beyond iron: metal-binding activity of the Pseudomonas quinolone signal-motif. Organic & Biomolecular Chemistry. 2023 Mai 30;21(25):5158-5163. doi: 10.1039/d3ob00710c

Ghatage T, Singh S, Mandal K, Jadhav KB, Dhar A. Activation of Mas and pGCA receptor pathways protects renal epithelial cell damage against oxidative-stress-induced injury. Peptides. 2023 Apr;162:170959. doi: 10.1016/j.peptides.2023.170959

Strobl J, Kozak F, Kamalov M, Reichinger D, Kurzbach D , Becker CFW. Understanding Self-Assembly of Silica-Precipitating Peptides to Control Silica Particle Morphology. Advanced Materials. 2023 Mär 16;35(11):2207586. doi: 10.1002/adma.202207586

Grant PS, Cruz Meyrelles RJ, Gajsek O, Niederacher G , Maryasin B , Maulide N. Biomimetic Cationic Cyclopropanation Enables an Efficient Chemoenzymatic Synthesis of 6,8-Cycloeudesmanes. Journal of the American Chemical Society. 2023 Mär 15;145(10):5855-5863. doi: 10.1021/jacs.2c13116

Negroni M, Kurzbach D. Missing Pieces in Structure Puzzles: How Hyperpolarized NMR Spectroscopy Can Complement Structural Biology and Biochemistry. ChemBioChem. 2023 Mär 14;24(6):e202200703. doi: 10.1002/cbic.202200703

Lubec J, Hussein AM, Kalaba P, Feyissa DD, Arias-Sandoval E, Cybulska-Klosowicz A et al. Low-Affinity/High-Selectivity Dopamine Transport Inhibition Sufficient to Rescue Cognitive Functions in the Aging Rat. Biomolecules. 2023 Mär 3;13(3):467. doi: 10.3390/biom13030467

Reichinger D, Reithofer M, Hohagen M, Drinic M, Tobias J, Wiedermann U et al. A Biomimetic, Silaffin R5-Based Antigen Delivery Platform. Pharmaceutics. 2023 Jan;15(1):121. doi: 10.3390/pharmaceutics15010121

Angele CM , Kurzbach D, Epasto LM, Malitz T, Groß K. Designing an innovative learning environment for students: 'NMR for food profiling – long drink, short experiment'. in Carvalho GS, Alfonso AS, Anastácio Z, Testa, Papadouris, Hrsg., Fostering scientific citizenship in an uncertain world: (Proceedings of ESERA 2021), Part 5 / Strand 5. Band 7. Braga: University of Minho. 2022

Dowman LJ, Kulkarni SS, Alegre-Requena J, Giltrap AM, Norman AR, Sharma A et al. Site-selective photocatalytic functionalization of peptides and proteins at selenocysteine. Nature Communications. 2022 Nov 12;13(1):6885. doi: 10.1038/s41467-022-34530-z

Negroni M, Turhan E, Kress T, Ceillier M, Jannin S, Kurzbach D. Frémy's Salt as a Low-Persistence Hyperpolarization Agent: Efficient Dynamic Nuclear Polarization Plus Rapid Radical Scavenging. Journal of the American Chemical Society. 2022 Nov;144(45):20680-20686. doi: 10.1021/jacs.2c07960

Hengxi Z, Modenutti C, Nekkanti YPK, Denis M, Bermejo IA, Lefèbre J et al. Identification of the Allosteric Binding Site for Thiazolopyrimidine on the C-Type Lectin Langerin. ACS Chemical Biology. 2022 Okt 21;17(10):2728–2733. Epub 2022 Sep 26. doi: 10.1021/acschembio.2c00626

Kerul L, Schrems M, Schmid A, Meli R, Becker CFW, Bello C. Semisynthesis of Homogeneous, Active Granulocyte Colony-Stimulating Factor Glycoforms. Angewandte Chemie (International Edition). 2022 Sep 26;61(39):1-10. e202206116. doi: 10.1002/anie.202206116

Epasto LM, Honegger P, Che K, Kozak F, Jörg F, Schröder C et al. Nuclear Overhauser spectroscopy in hyperpolarized water - chemical vs. magnetic exchange. Chemical Communications. 2022 Sep;58(83):11661-11664. doi: 10.1039/d2cc03735a

Epasto LM, Che K, Kozak F, Selimovic A, Kaderavek P, Kurzbach D. Toward protein NMR at physiological concentrations by hyperpolarized water-Finding and mapping uncharted conformational spaces. Science Advances. 2022 Aug 5;8(31):eabq5179. doi: 10.1126/sciadv.abq5179

Reichinger D, Reithofer M, Drinic M, Jahn-Schmid B, Wiedermann-Schmidt U, Becker CFW. Developing biomimetic silica particles as antigen delivery tools and general adjuvants. Journal of Peptide Science. 2022 Aug;28(3):P022.

Dürrauer L, Gajsek O, Kravchuk A , Becker CFW, Buchner J, Nguyen T. IgM Assembly on the molecular level. Journal of Peptide Science. 2022 Aug;28(3):P451.

Schwarz P, Jadhav KB, Gotthardt D, Hendrikx T, Gruber C, Hellinger R. Nature-derived peptide inhibitors of prolyl oligopeptidase modulate T-cell proliferation. Journal of Peptide Science. 2022 Aug;28(3):P047.

Gattringer J, Jadhav KB, Hendrikx T, Gotthardt D, Gruber C, Hellinger R. Peptides as modulators of immune cell migration. Journal of Peptide Science. 2022 Aug;28(3):MS02.

Raabe K , Muttenthaler M. Photoactivatable probes to study long-term memory formation. Journal of Peptide Science. 2022 Aug;28(3):P443.

Jadhav KB, Vellan P, Niederacher G , Becker CFW , Muttenthaler M. Recombinant- and semi- synthesis of human trefoil factor 2 (hTFF2) protein and its analogues. Journal of Peptide Science. 2022 Aug;28(3):P429.

Publikationen Institut für Biologische Chemie (gegr. 2011)