Publikationen

Savchenko V , Szamosvári D , Bao Y , Pignitter M , Böttcher T. Biosynthetic flexibility of Pseudomonas aeruginosa leads to hydroxylated 2-alkylquinolones with proinflammatory host response. Communications Chemistry. 2023 Dez;6(1):138. doi: 10.1038/s42004-023-00937-y

Schwarz P, Jadhav KB, Gruber C, Hellinger R. Blood Brain Barrier - Peptide Shuttles For Drug Delivery Into The CNS. British Journal of Pharmacology. 2023 Okt 11;180(Supplement1):525-526. Meeting Abstract: P0666.

Perisic M , Kalaba P, Keimpema E, Muttenthaler M, Gruber C. Development and application of fluorescent oxytocin receptor tracers. British Journal of Pharmacology. 2023 Okt 11;180(Supplement1):694-694. Meeting Abstract: P0984.

Kalaba P, Pacher K, Neill PJ, Dragacevic V, Zehl M , Wackerlig J et al. Chirality Matters: Fine-Tuning of Novel Monoamine Reuptake Inhibitors Selectivity through Manipulation of Stereochemistry. Biomolecules. 2023 Sep;13(9):1415. doi: 10.3390/biom13091415

Schrems M, Kravchuk A, Niederacher G, Exler F, Bello C, Becker CFW. Light-Cleavable Auxiliary for Diselenide–Selenoester Ligations of Peptides and Proteins. Chemistry - A European Journal. 2023 Aug 15;29(46):e202301253. doi: 10.1002/chem.202301253

Kriegesmann J, Schlatzer T, Che K, Altdorf C, Huhmann S, Kählig H et al. Constraining and Modifying Peptides Using Pd-Mediated Cysteine Allylation. ChemBioChem. 2023 Jul 3;24(13):e202300098. doi: 10.1002/cbic.202300098

Mukherjee S , Vogl DP , Becker CFW. Site-Specific Glycation of Human Heat Shock Protein (Hsp27) Enhances Its Chaperone Activity. ACS Chemical Biology. 2023 Jul;18(8):1760-1771. doi: 10.1021/acschembio.3c00214

Bello C, Pranzini E, Piemontese E, Schrems M, Taddei ML, Giovannelli L et al. Chemoenzymatic Synthesis of Glycopeptides to Explore the Role of Mucin 1 Glycosylation in Cell Adhesion. ChemBioChem. 2023 Jun 15;24(12):e202200741. doi: 10.1002/cbic.202200741

Szamosvari D , Savchenko V, Badouin N, Böttcher T. Beyond iron: metal-binding activity of the Pseudomonas quinolone signal-motif. Organic & Biomolecular Chemistry. 2023 Mai 30;21(25):5158-5163. doi: 10.1039/d3ob00710c

Ghatage T, Singh S, Mandal K, Jadhav KB, Dhar A. Activation of Mas and pGCA receptor pathways protects renal epithelial cell damage against oxidative-stress-induced injury. Peptides. 2023 Apr;162:170959. doi: 10.1016/j.peptides.2023.170959

Strobl J, Kozak F, Kamalov M, Reichinger D, Kurzbach D , Becker CFW. Understanding Self-Assembly of Silica-Precipitating Peptides to Control Silica Particle Morphology. Advanced Materials. 2023 Mär 16;35(11):2207586. doi: 10.1002/adma.202207586

Negroni M, Kurzbach D. Missing Pieces in Structure Puzzles: How Hyperpolarized NMR Spectroscopy Can Complement Structural Biology and Biochemistry. ChemBioChem. 2023 Mär 14;24(6):e202200703. doi: 10.1002/cbic.202200703

Lubec J, Hussein AM , Kalaba P, Feyissa DD, Arias-Sandoval E, Cybulska-Klosowicz A et al. Low-Affinity/High-Selectivity Dopamine Transport Inhibition Sufficient to Rescue Cognitive Functions in the Aging Rat. Biomolecules. 2023 Mär 3;13(3):467. doi: 10.3390/biom13030467

Reichinger D, Reithofer M, Hohagen M, Drinic M, Tobias J, Wiedermann U et al. A Biomimetic, Silaffin R5-Based Antigen Delivery Platform. Pharmaceutics. 2023 Jan;15(1):121. doi: 10.3390/pharmaceutics15010121

Turhan E , Pötzl C, Keil W, Negroni M, Kouřil K, Meier B et al. Biphasic NMR of Hyperpolarized Suspensions-Real-Time Monitoring of Solute-to-Solid Conversion to Watch Materials Grow. The Journal of Physical Chemistry Part C (Nanomaterials and Interfaces). 2023;127(39):19591-19598. doi: 10.1021/acs.jpcc.3c04198

Angele CM , Kurzbach D, Epasto LM, Malitz T, Groß K. Designing an innovative learning environment for students: 'NMR for food profiling – long drink, short experiment'. in Carvalho GS, Alfonso AS, Anastácio Z, Testa, Papadouris, Hrsg., Fostering scientific citizenship in an uncertain world: (Proceedings of ESERA 2021), Part 5 / Strand 5. Band 7. Braga: University of Minho. 2022

Dowman LJ, Kulkarni SS, Alegre-Requena J, Giltrap AM, Norman AR, Sharma A et al. Site-selective photocatalytic functionalization of peptides and proteins at selenocysteine. Nature Communications. 2022 Nov 12;13(1):6885. doi: 10.1038/s41467-022-34530-z

Negroni M, Turhan E, Kress T, Ceillier M, Jannin S, Kurzbach D. Frémy's Salt as a Low-Persistence Hyperpolarization Agent: Efficient Dynamic Nuclear Polarization Plus Rapid Radical Scavenging. Journal of the American Chemical Society. 2022 Nov;144(45):20680-20686. doi: 10.1021/jacs.2c07960

Hengxi Z, Modenutti C, Nekkanti YPK, Denis M, Bermejo IA, Lefèbre J et al. Identification of the Allosteric Binding Site for Thiazolopyrimidine on the C-Type Lectin Langerin. ACS Chemical Biology. 2022 Okt 21;17(10):2728–2733. Epub 2022 Sep 26. doi: 10.1021/acschembio.2c00626

Kerul L, Schrems M, Schmid A, Meli R, Becker CFW, Bello C. Semisynthesis of Homogeneous, Active Granulocyte Colony-Stimulating Factor Glycoforms. Angewandte Chemie (International Edition). 2022 Sep 26;61(39):1-10. e202206116. doi: 10.1002/anie.202206116

Epasto LM, Honegger P, Che K, Kozak F, Jörg F, Schröder C et al. Nuclear Overhauser spectroscopy in hyperpolarized water - chemical vs. magnetic exchange. Chemical Communications. 2022 Sep;58(83):11661-11664. doi: 10.1039/d2cc03735a

Epasto LM, Che K, Kozak F, Selimovic A, Kaderavek P, Kurzbach D. Toward protein NMR at physiological concentrations by hyperpolarized water-Finding and mapping uncharted conformational spaces. Science Advances. 2022 Aug 5;8(31):eabq5179. doi: 10.1126/sciadv.abq5179

Reichinger D, Reithofer M, Drinic M, Jahn-Schmid B, Wiedermann-Schmidt U, Becker CFW. Developing biomimetic silica particles as antigen delivery tools and general adjuvants. Journal of Peptide Science. 2022 Aug;28(3):P022.

Dürrauer L, Gajsek O , Kravchuk A , Becker CFW, Buchner J, Nguyen T. IgM Assembly on the molecular level. Journal of Peptide Science. 2022 Aug;28(3):P451.

Schwarz P, Jadhav KB, Gotthardt D, Hendrikx T, Gruber C, Hellinger R. Nature-derived peptide inhibitors of prolyl oligopeptidase modulate T-cell proliferation. Journal of Peptide Science. 2022 Aug;28(3):P047.

Gattringer J, Jadhav KB, Hendrikx T, Gotthardt D, Gruber C, Hellinger R. Peptides as modulators of immune cell migration. Journal of Peptide Science. 2022 Aug;28(3):MS02.

Raabe K , Muttenthaler M. Photoactivatable probes to study long-term memory formation. Journal of Peptide Science. 2022 Aug;28(3):P443.

Jadhav KB, Vellan P, Niederacher G, Becker CFW , Muttenthaler M. Recombinant- and semi- synthesis of human trefoil factor 2 (hTFF2) protein and its analogues. Journal of Peptide Science. 2022 Aug;28(3):P429.

Schrems M, Bello C, Becker CFW. Synthesis of a Selenium-based LigationAuxiliary for Traceless Peptide Ligations. Journal of Peptide Science. 2022 Aug;28(3):P441.

Huhmann S, Kujundzic M, Niederacher G, Becker CFW. Tailor-made ubiquitin chains for targeting the UPS or autophagy. Journal of Peptide Science. 2022 Aug;28(3):O27.

Perisic M , Kalaba P, Keimpema E, Gruber C, Muttenthaler M. Tracer development for oxytocin receptor imaging. Journal of Peptide Science. 2022 Aug;28(3):P285.

Hering A, Emidio NB, Muttenthaler M. Expanding the versatility and scope of the oxime ligation: rapid bioconjugation to disulfide-rich peptides. Chemical Communications. 2022 Jul 26;58(65):9100-9103. doi: 10.1039/d2cc03752a

Kouhnavardi S, Ecevitoglu A, Dragacevic V, Sanna F, Arias-Sandoval E, Kalaba P et al. A Novel and Selective Dopamine Transporter Inhibitor, (S)-MK-26, Promotes Hippocampal Synaptic Plasticity and Restores Effort-Related Motivational Dysfunctions. Biomolecules. 2022 Jul;12(7):881. doi: 10.3390/biom12070881

Liu H, Muttenthaler M. High Oxytocin Receptor Expression Linked to Increased Cell Migration and Reduced Survival in Patients with Triple-Negative Breast Cancer. Biomedicines. 2022 Jul;10(7):1595. doi: 10.3390/biomedicines10071595

Hering A, Jieu B, Jones A, Muttenthaler M. Approaches to Improve the Quantitation of Oxytocin in Human Serum by Mass Spectrometry. Frontiers in Chemistry. 2022 Jun 9;10:889154. doi: 10.3389/fchem.2022.889154

Negroni M, Guarin D, Che K, Epasto LM, Turhan E, Selimovic A et al. Inversion of Hyperpolarized ¹³C NMR Signals through Cross-Correlated Cross-Relaxation in Dissolution DNP Experiments. Journal of Physical Chemistry B. 2022 Jun 8;126(24):4599-4610. doi: 10.1021/acs.jpcb.2c03375

Kulkarni SS, Watson EE, Maxwell JWC, Niederacher G, Johansen-Leete J, Huhmann S et al. Expressed Protein Selenoester Ligation. Angewandte Chemie (International Edition). 2022 Mai 9;61(20):e202200163. doi: 10.1002/anie.202200163

Hilty C, Kurzbach D, Frydman L. Hyperpolarized water as universal sensitivity booster in biomolecular NMR. Nature Protocols. 2022 Mai;17(7):1621-1657. doi: 10.1038/s41596-022-00693-8

Kremsmayr T, Aljnabi A, Blanco-Canosa JB, Tran HNT, Emidio NB, Muttenthaler M. On the Utility of Chemical Strategies to Improve Peptide Gut Stability. Journal of Medicinal Chemistry. 2022 Apr 28;65(8):6191-6206. doi: 10.1021/acs.jmedchem.2c00094

Hanna C, Kriegesmann J, Dowman L, Becker C, Payne RJ. Chemical Synthesis and Semisynthesis of Lipidated Proteins. Angewandte Chemie (International Edition). 2022 Apr 4;61(15):e202111266. doi: 10.1002/anie.202111266

Schmid P, Peñalver L, Böttcher T. A ligand selection strategy to customize small molecule probes for activity-based protein profiling (LS-ABPP). in Carlson EE, Hrsg., Chemical Microbiology Part A. Elsevier. 2022. S. 23-58. (Methods in Enzymology, Band 664). doi: 10.1016/bs.mie.2022.01.008

Kremsmayr T, Muttenthaler M. Fmoc Solid Phase Peptide Synthesis of Oxytocin and Analogues. in Werry EL, Reekie TA, Kassiou M, Hrsg., Oxytocin: Methods and Protocols. 1 Aufl. Band 2384. Humana Press, Springer. 2022. S. 175-199. (Methods in Molecular Biology, Band 2384). doi: 10.1007/978-1-0716-1759-5_11

Klein K, Garkov D, Rütschlin S, Böttcher T, Schreiber F. QSDB—a graphical Quorum Sensing Database. Database: The Journal of Biological Databases and Curation. 2021 Nov 26;2021:baab058. doi: 10.1093/database/baab058

Klein K, Garkov D, Ruetschlin S, Boettcher T, Schreiber F. QSDB-a graphical Quorum Sensing Database (vol 2021, baab058, 2021). Database: The Journal of Biological Databases and Curation. 2021 Nov 26;2021:baab071. doi: 10.1093/database/baab071

Böttcher T, Nguyen THN, Szamosvari D. Synthesis of bacterial 2-alkyl-4(1H)-quinolone derivatives. ARKIVOC. 2021 Nov 12;2021(9):218-239. doi: 10.24820/ark.5550190.p011.547

Muratspahic E, Retzl B, Dürrauer L, Freissmuth M , Becker CFW, Gruber CW. Genome Mining-Based Discovery of Blenny Fish-Derived Peptides Targeting the Mouse κ-Opioid Receptor. Frontiers in Pharmacology. 2021 Okt 22;12:773029. doi: 10.3389/fphar.2021.773029

Negroni M, Kurzbach D. Residue-resolved monitoring of protein hyperpolarization at sub-second time resolution. Communications Chemistry. 2021 Okt 22;4(1):147. doi: 10.1038/s42004-021-00587-y

von Baeckmann C, Rubio GMDM, Kaehlig H , Kurzbach D , Reithofer MR , Kleitz F. Evaporation-Induced Self-Assembly of Small Peptide-Conjugated Silica Nanoparticles. Angewandte Chemie (International Edition). 2021 Okt 11;60(42):22700-22705. Epub 2021 Sep 14. doi: 10.1002/anie.202108378

Bialas F, Reichinger D, Becker CFW. Biomimetic and biopolymer-based enzyme encapsulation. Enzyme and microbial Technology. 2021 Okt;150:109864. doi: 10.1016/j.enzmictec.2021.109864

Baumgartner M, Lang M, Holley H, Crepaz D, Hausmann B, Pjevac P et al. Mucosal Biofilms Are an Endoscopic Feature of Irritable Bowel Syndrome and Ulcerative Colitis. Gastroenterology. 2021 Okt;161(4):1245-1256. Epub 2021 Jun 16. doi: 10.1053/j.gastro.2021.06.024

Publikationen Institut für Biologische Chemie (gegr. 2011)