Publikationen

Turhan E, Minaei M, Narwal P, Meier B, Kouřil K, Kurzbach D. Short-lived calcium carbonate precursors observed in situ via Bullet-dynamic nuclear polarization. Communications Chemistry. 2024 Dez;7(1):210. doi: 10.1038/s42004-024-01300-5

Pereira FC, Ge X, Kristensen JM, Kirkegaard RH, Maritsch K, Szamosvári D et al. The Parkinson's disease drug entacapone disrupts gut microbiome homoeostasis via iron sequestration. Nature Microbiology. 2024 Dez;9(12):3165–3183. Epub 2024 Nov 21. doi: 10.1038/s41564-024-01853-0

Baldensperger T, Jung T, Heinze T, Schwerdtle T, Höhn A, Grune T. The age pigment lipofuscin causes oxidative stress, lysosomal dysfunction, and pyroptotic cell death. Free Radical Biology and Medicine. 2024 Nov 20;225:871-880. doi: 10.1016/j.freeradbiomed.2024.10.311

Jandl B, Dighe S, Baumgartner M, Makristathis A, Gasche C, Muttenthaler M. Gastrointestinal Biofilms: Endoscopic Detection, Disease Relevance, and Therapeutic Strategies. Gastroenterology. 2024 Nov;167(6):1098-1112.e5. doi: 10.1053/j.gastro.2024.04.032

Kremsmayr T, Schober G, Kaltenböck M, Hoare BL, Brierley SM, Muttenthaler M. Oxytocin Analogues for the Oral Treatment of Abdominal Pain. Angewandte Chemie - International Edition. 2024 Nov. Epub 2024 Nov. doi: 10.1002/anie.202415333

Turhan E, Goldberga I, Pötzl C, Keil W, Guigner JM, Haßler MFT et al. Branched Polymeric Prenucleation Assemblies Initiate Calcium Phosphate Precipitation. Journal of the American Chemical Society. 2024 Sep 18;146(37):25614-25624. Epub 2024. doi: 10.1021/jacs.4c07325

Jandl B, Dighe S, Gasche C, Makristathis A, Muttenthaler M. Intestinal biofilms: pathophysiological relevance, host defense, and therapeutic opportunities. Clinical microbiology reviews. 2024 Sep 12;37(3):e0013323. 00133-23. Epub 2024 Jul 12. doi: 10.1128/cmr.00133-23

Jandl B, Zheng R, Muttenthaler M, Baell J. Novel Diacyl-hydrazide Compounds as Potential Therapeutics for Visceral Leishmaniasis. ACS Omega. 2024 Sep 3;9(35):37170-37182. Epub 2024 Aug 22. doi: 10.1021/acsomega.4c04517

Steuer J, Sinn M, Eble F, Rütschlin S, Böttcher T, Hartig JS et al. Cooperative binding of bivalent ligands yields new insights into the guanidine-II riboswitch. NAR Genomics and Bioinformatics. 2024 Sep 1;6(3):lqae132. doi: 10.1093/nargab/lqae132

Muttenthaler M. CHEMICAL STRATEGIES TO TUNE POTENCY, SELECTIVITY AND STABILITY OF VENOM PEPTIDES. Toxicon. 2024 Sep;248:108028.

Savchenko V, Jaegers M, Rasche R, Herrmann E, König S, Kümmel D et al. Unraveling key steps in the biosynthesis of antimicrobial methylated unsaturated 2-alkyl-4-quinolones of Burkholderia thailandensis. Cell Reports Physical Science. 2024 Aug 21;5(8):102100. Epub 2024 Jul 10. doi: 10.1016/j.xcrp.2024.102100

Kozak F, Brandis D , Pötzl C, Epasto LM, Reichinger D, Obrist D et al. An Atomistic View on the Mechanism of Diatom Peptide-Guided Biomimetic Silica Formation. Advanced science. 2024 Aug 14;11(30):2401239. Epub 2024. doi: 10.1002/advs.202401239

Perisic M, Kalaba P, Keimpema E, Gruber CW, Muttenthaler M. Advanced molecular tools to study the oxytocin receptor. Journal of Peptide Science. 2024 Aug;30(Suppl. 2):YML05.

Kozak F, Brandis D , Pötzl C, Epasto LM, Reichinger D, Polyansky A et al. An atomistic view on the mechanism of diatom peptide-guided biomimetic silica formation. Journal of Peptide Science. 2024 Aug;30(Suppl. 2):507-P1.299. doi: 10.1002/psc.3642

Schwarz P, Jadhav KB, Gruber CW, Hellinger R. Blood brain barrier-peptide shuttles for drug delivery into the CNS. Journal of Peptide Science. 2024 Aug;30(Suppl. 2):246-P1.

Gattringer J, Weidmann A, Jadhav KB, Gruber CW, Hellinger R. Cyclic peptide modulators of lymphocyte migration for the treatment of autoimmune disorders. Journal of Peptide Science. 2024 Aug;30(Suppl. 2):421-P1.089.

Jandl B, Lang M, Makristathis A, Gasche C, Muttenthaler M. Development of gut-restricted antibiofilm peptides to target gastrointestinal biofilms. Journal of Peptide Science. 2024 Aug;30(Suppl. 2):248-P1.134.

Back HS , Felkl M , Becker CFW. Fine-tuning the immunestimulatory and cancer cell binding properties of immune system engagers (ISErs). Journal of Peptide Science. 2024 Aug;30(Suppl. 2):163-P1.125.

Brandis D, Kozak F, Becker CFW , Kurzbach D. Methyl-based nuclear magnetic resonance methods for characterization of large peptide self-assemblies. Journal of Peptide Science. 2024 Aug;30(Suppl. 2):504-P1.298.

Urschbach M, Huhmann S, Ferrari L, Vogl DP, Niederacher G , Martens S et al. Modular access to structurally defined ubiquitin chains. Journal of Peptide Science. 2024 Aug;30(Suppl. 2):831-P2.

Raabe K, Kalaba P, Yong XLH, Keimpema E, Anggono V, Muttenthaler M. Photocontrollable probes for the investigation of neuropeptide signalling. Journal of Peptide Science. 2024 Aug;30(Suppl. 2):382-P1.

Vogl DP, Becker CFW , Preißler M. Site-specific post-translational modifications of Tau4. Journal of Peptide Science. 2024 Aug;30(Suppl. 2):527-P1.

Schmied SH, Mukherjee S, Becker CFW. Unraveling the functional implications of site-specific phosphorylations on heat shock protein 27: a semisynthetic approach. Journal of Peptide Science. 2024 Aug;30(Suppl. 2):360-P1.

Becker CFW. Zooming into posttranslational modifications by protein semi-synthesis. Journal of Peptide Science. 2024 Aug;30(Suppl. 2):L83.

Zachrdla M , Turhan E , Pötzl C, Sadet A, Vasos PR, Kurzbach D. Hyperpolarized nuclear Overhauser enhancement of alanine methyl groups by doubly relayed proton exchange. Journal of Magnetic Resonance. 2024 Jul;364:107727. doi: 10.1016/j.jmr.2024.107727

Tomašević N, Emser FS, Muratspahić E, Gattringer J, Hasinger S, Hellinger R et al. Discovery and development of macrocyclic peptide modulators of the cannabinoid 2 receptor. Journal of Biological Chemistry. 2024 Jun;300(6):107330. doi: 10.1016/j.jbc.2024.107330

Epasto LM, Maimbourg T, Rosso A, Kurzbach D. Unified understanding of the breakdown of thermal mixing dynamic nuclear polarization: The role of temperature and radical concentration. Journal of Magnetic Resonance. 2024 Mai;362:107670. doi: 10.1016/j.jmr.2024.107670

Schmid A, Bello C, Becker CFW. Synthesis of N-Glycosylated Soluble Fas Ligand. Chemistry - A European Journal. 2024 Apr 25;30(24):e202400120. Epub 2024 Feb 16. doi: 10.1002/chem.202400120

Perisic M, Woolcock K, Hering A, Mendel H, Muttenthaler M. Oxytocin and vasopressin signaling in health and disease. Trends in Biochemical Sciences. 2024 Apr;49(4):361-377. doi: 10.1016/j.tibs.2024.01.010

Mengrelis K, Niederacher G, Prickler L, Kainz V, Weijler AM, Rudolph E et al. Coupling of a Major Allergen to the Surface of Immune Cells for Use in Prophylactic Cell Therapy for the Prevention of IgE-Mediated Allergy. Cells. 2024 Mär;13(5):446. doi: 10.3390/cells13050446

Vogl DP, Mateos B, Migotti M , Felkl M, Conibear AC, Konrat R et al. Semisynthesis of segmentally isotope-labeled and site-specifically palmitoylated CD44 cytoplasmic tail. Bioorganic and Medicinal Chemistry. 2024 Feb 15;100:117617. doi: 10.1016/j.bmc.2024.117617

Kalaba P, Sanchez de la Rosa C, Möller A, Alewood PF, Muttenthaler M. Targeting the Oxytocin Receptor for Breast Cancer Management: A Niche for Peptide Tracers. Journal of Medicinal Chemistry. 2024 Feb 8;67(3):1625-1640. doi: 10.1021/acs.jmedchem.3c01089

Epasto LM, Pötzl C , Peterlik H, Khalil M, Saint-Pierre C, Gasparutto D et al. NMR-identification of the interaction between BRCA1 and the intrinsically disordered monomer of the Myc-associated factor X. Protein Science. 2024 Jan;33(1):e4849. doi: 10.1002/pro.4849

Orgler E, Baumgartner M, Duller S, Kumptisch C, Hausmann B, Moser D et al. Archaea influence composition of endoscopically visible ileocolonic biofilms. Gut microbes. 2024;16(1):2359500. doi: 10.1080/19490976.2024.2359500

Mou S, Savchenko V, Filz V , Böttcher T, DeShazer D. Burkholderia pseudomallei produces 2-alkylquinolone derivatives important for host virulence and competition with bacteria that employ naphthoquinones for aerobic respiration. Frontiers in Microbiology. 2024;15:1474033. doi: 10.3389/fmicb.2024.1474033

Gajsek O, Becker CFW, Conibear AC. Site-specifically Phosphorylated Hsp90C-terminal Domain Variants Provide Access to Deciphering the Chaperone Code. Chemistry - A European Journal. 2024. Epub 2024. doi: 10.1002/chem.202403676

Kratzwald S, Schwarz TC, Ledolter K, Hlavac M, Felkl M , Becker CFW et al. Synthesis of a ¹³C/²H Labeled Building Block to Probe the Phosphotyrosine Interactome Using Biomolecular NMR Spectroscopy. ChemBioChem. 2024. Epub 2024. doi: 10.1002/cbic.202400663

Savchenko V, Szamosvári D , Bao Y , Pignitter M , Böttcher T. Biosynthetic flexibility of Pseudomonas aeruginosa leads to hydroxylated 2-alkylquinolones with proinflammatory host response. Communications Chemistry. 2023 Dez;6(1):138. doi: 10.1038/s42004-023-00937-y

Dunajova Z, Mateu BP, Radler P, Lim K, Brandis D, Velicky P et al. Chiral and nematic phases of flexible active filaments. Nature Physics. 2023 Dez;19(12):1916-1926. doi: 10.1038/s41567-023-02218-w

Spreitzer I, Keife J, Strasser T, Kalaba P, Lubec J, Neuhaus W et al. Pharmacokinetics of Novel Dopamine Transporter Inhibitor CE-123 and Modafinil with a Focus on Central Nervous System Distribution. International Journal of Molecular Sciences. 2023 Dez;24(23):16956. doi: 10.3390/ijms242316956

Muratspahić E, Deibler K, Han J, Tomašević N, Jadhav KB, Olivé-Marti AL et al. Design and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptor. Nature Communications. 2023 Nov 28;14(1):8064. doi: 10.1038/s41467-023-43718-w

Wirth U, Raabe K, Kalaba P, Keimpema E, Muttenthaler M, König B. Photoswitchable Probes of Oxytocin and Vasopressin. Journal of Medicinal Chemistry. 2023 Nov 9;66(21):14853-14865. doi: 10.1021/acs.jmedchem.3c01415

Schwarz P, Jadhav KB, Gruber C, Hellinger R. Blood Brain Barrier - Peptide Shuttles For Drug Delivery Into The CNS. British Journal of Pharmacology. 2023 Okt 11;180(Supplement1):525-526. Meeting Abstract: P0666.

Perisic M, Kalaba P, Keimpema E, Muttenthaler M, Gruber C. Development and application of fluorescent oxytocin receptor tracers. British Journal of Pharmacology. 2023 Okt 11;180(Supplement1):694-694. Meeting Abstract: P0984.

Turhan E , Pötzl C, Keil W, Negroni M, Kouřil K, Meier B et al. Biphasic NMR of Hyperpolarized Suspensions-Real-Time Monitoring of Solute-to-Solid Conversion to Watch Materials Grow. The Journal of Physical Chemistry Part C (Nanomaterials and Interfaces). 2023 Okt 5;127(39):19591-19598. doi: 10.1021/acs.jpcc.3c04198

Ückert AK, Rütschlin S, Gutbier S, Wörz NC, Miah MR, Martins AC et al. Identification of the bacterial metabolite aerugine as potential trigger of human dopaminergic neurodegeneration. Environment International. 2023 Okt 3;180:108229. doi: 10.1016/j.envint.2023.108229

Kalaba P, Pacher K, Neill PJ, Dragacevic V, Zehl M , Wackerlig J et al. Chirality Matters: Fine-Tuning of Novel Monoamine Reuptake Inhibitors Selectivity through Manipulation of Stereochemistry. Biomolecules. 2023 Sep;13(9):1415. doi: 10.3390/biom13091415

Schrems M, Kravchuk A , Niederacher G , Exler F, Bello C, Becker CFW. Light-Cleavable Auxiliary for Diselenide–Selenoester Ligations of Peptides and Proteins. Chemistry - A European Journal. 2023 Aug 15;29(46):e202301253. doi: 10.1002/chem.202301253

Kriegesmann J, Schlatzer T, Che K, Altdorf C, Huhmann S, Kählig H et al. Constraining and Modifying Peptides Using Pd-Mediated Cysteine Allylation. ChemBioChem. 2023 Jul 3;24(13):e202300098. doi: 10.1002/cbic.202300098

Mukherjee S, Vogl DP, Becker CFW. Site-Specific Glycation of Human Heat Shock Protein (Hsp27) Enhances Its Chaperone Activity. ACS Chemical Biology. 2023 Jul;18(8):1760-1771. doi: 10.1021/acschembio.3c00214

Publikationen Institut für Biologische Chemie (gegr. 2011)