Publikationen Institut für Biologische Chemie (gegr. 2011)
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Ückert AK, Rütschlin S, Gutbier S, Wörz NC, Miah MR, Martins AC et al. Identification of the bacterial metabolite aerugine as potential trigger of human dopaminergic neurodegeneration. Environment International. 2023 Okt 3;180:108229. doi: 10.1016/j.envint.2023.108229
Kalaba P, Pacher K, Neill PJ, Dragacevic V, Zehl M, Wackerlig J et al. Chirality Matters: Fine-Tuning of Novel Monoamine Reuptake Inhibitors Selectivity through Manipulation of Stereochemistry. Biomolecules. 2023 Sep;13(9):1415. doi: 10.3390/biom13091415
Schrems M, Kravchuk A, Niederacher G, Exler F, Bello C, Becker CFW. Light-Cleavable Auxiliary for Diselenide–Selenoester Ligations of Peptides and Proteins. Chemistry - A European Journal. 2023 Aug 15;29(46):e202301253. doi: 10.1002/chem.202301253
Kriegesmann J, Schlatzer T, Che K, Altdorf C, Huhmann S, Kählig H et al. Constraining and Modifying Peptides Using Pd-Mediated Cysteine Allylation. ChemBioChem. 2023 Jul 3;24(13):e202300098. doi: 10.1002/cbic.202300098
Mukherjee S, Vogl DP, Becker CFW. Site-Specific Glycation of Human Heat Shock Protein (Hsp27) Enhances Its Chaperone Activity. ACS Chemical Biology. 2023 Jul;18(8):1760-1771. doi: 10.1021/acschembio.3c00214
Bello C, Pranzini E, Piemontese E, Schrems M, Taddei ML, Giovannelli L et al. Chemoenzymatic Synthesis of Glycopeptides to Explore the Role of Mucin 1 Glycosylation in Cell Adhesion. ChemBioChem. 2023 Jun 15;24(12):e202200741. doi: 10.1002/cbic.202200741
Szamosvari D, Savchenko V, Badouin N, Böttcher T. Beyond iron: metal-binding activity of the Pseudomonas quinolone signal-motif. Organic & Biomolecular Chemistry. 2023 Mai 30;21(25):5158-5163. doi: 10.1039/d3ob00710c
Ghatage T, Singh S, Mandal K, Jadhav KB, Dhar A. Activation of Mas and pGCA receptor pathways protects renal epithelial cell damage against oxidative-stress-induced injury. Peptides. 2023 Apr;162:170959. doi: 10.1016/j.peptides.2023.170959
Strobl J, Kozak F, Kamalov M, Reichinger D, Kurzbach D, Becker CFW. Understanding Self-Assembly of Silica-Precipitating Peptides to Control Silica Particle Morphology. Advanced Materials. 2023 Mär 16;35(11):2207586. doi: 10.1002/adma.202207586
Grant PS, Cruz Meyrelles RJ, Gajsek O, Niederacher G, Maryasin B, Maulide N. Biomimetic Cationic Cyclopropanation Enables an Efficient Chemoenzymatic Synthesis of 6,8-Cycloeudesmanes. Journal of the American Chemical Society. 2023 Mär 15;145(10):5855-5863. doi: 10.1021/jacs.2c13116
Negroni M, Kurzbach D. Missing Pieces in Structure Puzzles: How Hyperpolarized NMR Spectroscopy Can Complement Structural Biology and Biochemistry. ChemBioChem. 2023 Mär 14;24(6):e202200703. doi: 10.1002/cbic.202200703
Lubec J, Hussein AM, Kalaba P, Feyissa DD, Arias-Sandoval E, Cybulska-Klosowicz A et al. Low-Affinity/High-Selectivity Dopamine Transport Inhibition Sufficient to Rescue Cognitive Functions in the Aging Rat. Biomolecules. 2023 Mär 3;13(3):467. doi: 10.3390/biom13030467
Reichinger D, Reithofer M, Hohagen M, Drinic M, Tobias J, Wiedermann U et al. A Biomimetic, Silaffin R5-Based Antigen Delivery Platform. Pharmaceutics. 2023 Jan;15(1):121. doi: 10.3390/pharmaceutics15010121
Angele CM, Kurzbach D, Epasto LM, Malitz T, Groß K. Designing an innovative learning environment for students: 'NMR for food profiling – long drink, short experiment'. in Carvalho GS, Alfonso AS, Anastácio Z, Testa, Papadouris, Hrsg., Fostering scientific citizenship in an uncertain world: (Proceedings of ESERA 2021), Part 5 / Strand 5. Band 7. Braga: University of Minho. 2022
Dowman LJ, Kulkarni SS, Alegre-Requena J, Giltrap AM, Norman AR, Sharma A et al. Site-selective photocatalytic functionalization of peptides and proteins at selenocysteine. Nature Communications. 2022 Nov 12;13(1):6885. doi: 10.1038/s41467-022-34530-z
Negroni M, Turhan E, Kress T, Ceillier M, Jannin S, Kurzbach D. Frémy's Salt as a Low-Persistence Hyperpolarization Agent: Efficient Dynamic Nuclear Polarization Plus Rapid Radical Scavenging. Journal of the American Chemical Society. 2022 Nov;144(45):20680-20686. doi: 10.1021/jacs.2c07960
Hengxi Z, Modenutti C, Nekkanti YPK, Denis M, Bermejo IA, Lefèbre J et al. Identification of the Allosteric Binding Site for Thiazolopyrimidine on the C-Type Lectin Langerin. ACS Chemical Biology. 2022 Okt 21;17(10):2728–2733. Epub 2022 Sep 26. doi: 10.1021/acschembio.2c00626
Kerul L, Schrems M, Schmid A, Meli R, Becker CFW, Bello C. Semisynthesis of Homogeneous, Active Granulocyte Colony-Stimulating Factor Glycoforms. Angewandte Chemie (International Edition). 2022 Sep 26;61(39):1-10. e202206116. doi: 10.1002/anie.202206116
Epasto LM, Honegger P, Che K, Kozak F, Jörg F, Schröder C et al. Nuclear Overhauser spectroscopy in hyperpolarized water - chemical vs. magnetic exchange. Chemical Communications. 2022 Sep;58(83):11661-11664. doi: 10.1039/d2cc03735a
Epasto LM, Che K, Kozak F, Selimovic A, Kaderavek P, Kurzbach D. Toward protein NMR at physiological concentrations by hyperpolarized water-Finding and mapping uncharted conformational spaces. Science Advances. 2022 Aug 5;8(31):eabq5179. doi: 10.1126/sciadv.abq5179
Reichinger D, Reithofer M, Drinic M, Jahn-Schmid B, Wiedermann-Schmidt U, Becker CFW. Developing biomimetic silica particles as antigen delivery tools and general adjuvants. Journal of Peptide Science. 2022 Aug;28(3):P022.
Dürrauer L, Gajsek O, Kravchuk A, Becker CFW, Buchner J, Nguyen T. IgM Assembly on the molecular level. Journal of Peptide Science. 2022 Aug;28(3):P451.
Schwarz P, Jadhav KB, Gotthardt D, Hendrikx T, Gruber C, Hellinger R. Nature-derived peptide inhibitors of prolyl oligopeptidase modulate T-cell proliferation. Journal of Peptide Science. 2022 Aug;28(3):P047.
Gattringer J, Jadhav KB, Hendrikx T, Gotthardt D, Gruber C, Hellinger R. Peptides as modulators of immune cell migration. Journal of Peptide Science. 2022 Aug;28(3):MS02.
Raabe K, Muttenthaler M. Photoactivatable probes to study long-term memory formation. Journal of Peptide Science. 2022 Aug;28(3):P443.
Jadhav KB, Vellan P, Niederacher G, Becker CFW, Muttenthaler M. Recombinant- and semi- synthesis of human trefoil factor 2 (hTFF2) protein and its analogues. Journal of Peptide Science. 2022 Aug;28(3):P429.
Schrems M, Bello C, Becker CFW. Synthesis of a Selenium-based LigationAuxiliary for Traceless Peptide Ligations. Journal of Peptide Science. 2022 Aug;28(3):P441.
Huhmann S, Kujundzic M, Niederacher G, Becker CFW. Tailor-made ubiquitin chains for targeting the UPS or autophagy. Journal of Peptide Science. 2022 Aug;28(3):O27.
Perisic M, Kalaba P, Keimpema E, Gruber C, Muttenthaler M. Tracer development for oxytocin receptor imaging. Journal of Peptide Science. 2022 Aug;28(3):P285.
Hering A, Emidio NB, Muttenthaler M. Expanding the versatility and scope of the oxime ligation: rapid bioconjugation to disulfide-rich peptides. Chemical Communications. 2022 Jul 26;58(65):9100-9103. doi: 10.1039/d2cc03752a
Kouhnavardi S, Ecevitoglu A, Dragacevic V, Sanna F, Arias-Sandoval E, Kalaba P et al. A Novel and Selective Dopamine Transporter Inhibitor, (S)-MK-26, Promotes Hippocampal Synaptic Plasticity and Restores Effort-Related Motivational Dysfunctions. Biomolecules. 2022 Jul;12(7):881. doi: 10.3390/biom12070881
Liu H, Muttenthaler M. High Oxytocin Receptor Expression Linked to Increased Cell Migration and Reduced Survival in Patients with Triple-Negative Breast Cancer. Biomedicines. 2022 Jul;10(7):1595. doi: 10.3390/biomedicines10071595
Hering A, Jieu B, Jones A, Muttenthaler M. Approaches to Improve the Quantitation of Oxytocin in Human Serum by Mass Spectrometry. Frontiers in Chemistry. 2022 Jun 9;10:889154. doi: 10.3389/fchem.2022.889154
Negroni M, Guarin D, Che K, Epasto LM, Turhan E, Selimovic A et al. Inversion of Hyperpolarized
13C NMR Signals through Cross-Correlated Cross-Relaxation in Dissolution DNP Experiments. Journal of Physical Chemistry B. 2022 Jun 8;126(24):4599-4610. doi: 10.1021/acs.jpcb.2c03375
Kulkarni SS, Watson EE, Maxwell JWC, Niederacher G, Johansen-Leete J, Huhmann S et al. Expressed Protein Selenoester Ligation. Angewandte Chemie (International Edition). 2022 Mai 9;61(20):e202200163. doi: 10.1002/anie.202200163
Hilty C, Kurzbach D, Frydman L. Hyperpolarized water as universal sensitivity booster in biomolecular NMR. Nature Protocols. 2022 Mai;17(7):1621-1657. doi: 10.1038/s41596-022-00693-8
Kremsmayr T, Aljnabi A, Blanco-Canosa JB, Tran HNT, Emidio NB, Muttenthaler M. On the Utility of Chemical Strategies to Improve Peptide Gut Stability. Journal of Medicinal Chemistry. 2022 Apr 28;65(8):6191-6206. doi: 10.1021/acs.jmedchem.2c00094
Hanna C, Kriegesmann J, Dowman L, Becker C, Payne RJ. Chemical Synthesis and Semisynthesis of Lipidated Proteins. Angewandte Chemie (International Edition). 2022 Apr 4;61(15):e202111266. doi: 10.1002/anie.202111266
Schmid P, Peñalver L, Böttcher T. A ligand selection strategy to customize small molecule probes for activity-based protein profiling (LS-ABPP). in Carlson EE, Hrsg., Chemical Microbiology Part A. Elsevier. 2022. S. 23-58. (Methods in Enzymology, Band 664). doi: 10.1016/bs.mie.2022.01.008
Kremsmayr T, Muttenthaler M. Fmoc Solid Phase Peptide Synthesis of Oxytocin and Analogues. in Werry EL, Reekie TA, Kassiou M, Hrsg., Oxytocin: Methods and Protocols. 1 Aufl. Band 2384. Humana Press, Springer. 2022. S. 175-199. (Methods in Molecular Biology, Band 2384). doi: 10.1007/978-1-0716-1759-5_11
Klein K, Garkov D, Rütschlin S, Böttcher T, Schreiber F. QSDB—a graphical Quorum Sensing Database. Database: The Journal of Biological Databases and Curation. 2021 Nov 26;2021:baab058. doi: 10.1093/database/baab058
Klein K, Garkov D, Ruetschlin S, Boettcher T, Schreiber F. QSDB-a graphical Quorum Sensing Database (vol 2021, baab058, 2021). Database: The Journal of Biological Databases and Curation. 2021 Nov 26;2021:baab071. doi: 10.1093/database/baab071
Böttcher T, Nguyen THN, Szamosvari D. Synthesis of bacterial 2-alkyl-4(1H)-quinolone derivatives. ARKIVOC. 2021 Nov 12;2021(9):218-239. doi: 10.24820/ark.5550190.p011.547
Muratspahic E, Retzl B, Dürrauer L, Freissmuth M, Becker CFW, Gruber CW. Genome Mining-Based Discovery of Blenny Fish-Derived Peptides Targeting the Mouse κ-Opioid Receptor. Frontiers in Pharmacology. 2021 Okt 22;12:773029. doi: 10.3389/fphar.2021.773029
Negroni M, Kurzbach D. Residue-resolved monitoring of protein hyperpolarization at sub-second time resolution. Communications Chemistry. 2021 Okt 22;4(1):147. doi: 10.1038/s42004-021-00587-y
von Baeckmann C, Rubio GMDM, Kaehlig H, Kurzbach D, Reithofer MR, Kleitz F. Evaporation-Induced Self-Assembly of Small Peptide-Conjugated Silica Nanoparticles. Angewandte Chemie (International Edition). 2021 Okt 11;60(42):22700-22705. Epub 2021 Sep 14. doi: 10.1002/anie.202108378
Bialas F, Reichinger D, Becker CFW. Biomimetic and biopolymer-based enzyme encapsulation. Enzyme and microbial Technology. 2021 Okt;150:109864. doi: 10.1016/j.enzmictec.2021.109864
Baumgartner M, Lang M, Holley H, Crepaz D, Hausmann B, Pjevac P et al. Mucosal Biofilms Are an Endoscopic Feature of Irritable Bowel Syndrome and Ulcerative Colitis. Gastroenterology. 2021 Okt;161(4):1245-1256. Epub 2021 Jun 16. doi: 10.1053/j.gastro.2021.06.024
Bialas F, Becker CFW. Biomimetic Silica Encapsulation of Lipid Nanodiscs and β-Sheet-Stabilized Diacylglycerol Kinase. Bioconjugate Chemistry. 2021 Aug 18;32(8):1742-1752. doi: 10.1021/acs.bioconjchem.1c00260
Vogl DP, Conibear AC, Becker CFW. Segmental and site-specific isotope labelling strategies for structural analysis of posttranslationally modified proteins. RSC Chemical Biology. 2021 Aug;2(5):1441-1461. doi: 10.1039/d1cb00045d
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