Welcome to the Institute of Biological Chemistry, part of the Faculty of Chemistry at the University of Vienna. The institute provides an excellent environment for research at the interface of synthetic organic chemistry, molecular biology, biophysics and biomedicine. We combine chemical approaches, such as the synthesis of modified amino acids with solid phase peptide synthesis (SPPS) and biotechnological methods to address scientific challenges in the areas of protein biochemistry, neuropeptide research, biomaterials and medicine. Combining synthetic chemistry with molecular biology provides a unique opportunity to generate biomolecules that are not or not easily accessible by any other technique.

The resulting peptides and proteins carrying (posttranslational) modifications allow us to study specific biological questions, such as folding, activity and interaction with other biomolecules in vitro and in vivo. Biotechnological and biomedical applications of such chemically modified peptides, proteins and hybrid molecules are an important part of our research.

Furthermore, we are developing spectroscopic methods to characterize biomolecules. A special focus lies on dissolution dynamic nuclear polarization, a technique that enables the determination of high-resolution structures of proteins, peptides and bio-inorganic materials in real-time.

News

24.05.2022
 

Hyperpolarisiertes Wasser verstärkt Messsignale von Proteinen, DNA und Membranen

11.04.2022
 

Die NMR-Spektroskopie ist eine der wichtigsten Methoden, um Strukturen von Molekülen in Lösung zu ermitteln. Den Nutzen von NMR in Bezug auf...

01.04.2022
 

DoSChem awards with 26.000 Euro the joint expertise of Ludovica Martina Epasto (Institute of Biological Chemistry, Dennis Kurzbach group) and Miran...

24.03.2022
 

The Institute of Biological Chemistry, Department of Chemistry, University of Vienna is currently seeking a Ph.D. student with experience in the area...

10.01.2022
 

"Proteine sind die Funktionsmoleküle des Lebens und zählen neben Kohlenhydraten und Fetten zu den drei Hauptnährstoffen des Menschen“, sagt Christian...

07.07.2021
 

Die magnetische Kernresonanz (NMR) ist für viele Bereiche der Chemie von großer Bedeutung, da sie die leistungsstärkste Methode zur Aufklärung von...