Welcome to the Institute of Biological Chemistry, part of the Faculty of Chemistry at the University of Vienna. The institute provides an excellent environment for research at the interface of synthetic organic chemistry, molecular biology, biophysics and biomedicine. We combine chemical approaches, such as the synthesis of modified amino acids with solid phase peptide synthesis (SPPS) and biotechnological methods to address scientific challenges in the areas of protein biochemistry, neuropeptide research, biomaterials and medicine. Combining synthetic chemistry with molecular biology provides a unique opportunity to generate biomolecules that are not or not easily accessible by any other technique.

The resulting peptides and proteins carrying (posttranslational) modifications allow us to study specific biological questions, such as folding, activity and interaction with other biomolecules in vitro and in vivo. Biotechnological and biomedical applications of such chemically modified peptides, proteins and hybrid molecules are an important part of our research.

Furthermore, we are developing spectroscopic methods to characterize biomolecules. A special focus lies on dissolution dynamic nuclear polarization, a technique that enables the determination of high-resolution structures of proteins, peptides and bio-inorganic materials in real-time.



Milestone for therapeutic development of peptides against gastrointestinal disorders


Dennis Kurzbach von der Fakultät für Chemie baut gemeinsam mit seinem internationalen Team das erste dDNP-Setup Österreichs. Mit dieser innovativen...


Cutting-edge technology allows for real-time monitoring of biomineralisation as an important process of bone formation


How conotoxins can be used in pain therapy


An der TU Graz und Uni Wien entwickelte Methode führt zu besserem Verständnis natürlicher Proteinveränderungen und zur Verbesserung von...


Verändern Proteine im Körper ihre Struktur, können Krankheiten entstehen. ForscherInnen der Fakultät für Chemie und der Max F. Perutz Laboratories...