Publications Institut of Biological Chemistry (founded 2011)


Showing entries 1 - 50 out of 150
Muratspahić E, Deibler K, Han J, Tomašević N, Jadhav KB, Olivé-Marti AL et al. Design and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptor. Nature Communications. 2023 Dec;14(1):8064. doi: 10.1038/s41467-023-43718-w

Wirth U, Raabe K, Kalaba P, Keimpema E, Muttenthaler M, König B. Photoswitchable Probes of Oxytocin and Vasopressin. Journal of Medicinal Chemistry. 2023 Nov 9;66(21):14853-14865. doi: 10.1021/acs.jmedchem.3c01415

Ückert AK, Rütschlin S, Gutbier S, Wörz NC, Miah MR, Martins AC et al. Identification of the bacterial metabolite aerugine as potential trigger of human dopaminergic neurodegeneration. Environment International. 2023 Oct 3;180:108229. doi: 10.1016/j.envint.2023.108229

Kriegesmann J, Schlatzer T, Che K, Altdorf C, Huhmann S, Kählig H et al. Constraining and Modifying Peptides Using Pd-Mediated Cysteine Allylation. ChemBioChem. 2023 Jul 3;24(13):e202300098. doi: 10.1002/cbic.202300098

Mukherjee S, Vogl DP, Becker CFW. Site-Specific Glycation of Human Heat Shock Protein (Hsp27) Enhances Its Chaperone Activity. ACS Chemical Biology. 2023 Jul;18(8):1760-1771. doi: 10.1021/acschembio.3c00214

Bello C, Pranzini E, Piemontese E, Schrems M, Taddei ML, Giovannelli L et al. Chemoenzymatic Synthesis of Glycopeptides to Explore the Role of Mucin 1 Glycosylation in Cell Adhesion. ChemBioChem. 2023 Jun 15;24(12):e202200741. doi: 10.1002/cbic.202200741

Ghatage T, Singh S, Mandal K, Jadhav KB, Dhar A. Activation of Mas and pGCA receptor pathways protects renal epithelial cell damage against oxidative-stress-induced injury. Peptides. 2023 Apr;162:170959. doi: 10.1016/j.peptides.2023.170959

Lubec J, Hussein AM, Kalaba P, Feyissa DD, Arias-Sandoval E, Cybulska-Klosowicz A et al. Low-Affinity/High-Selectivity Dopamine Transport Inhibition Sufficient to Rescue Cognitive Functions in the Aging Rat. Biomolecules. 2023 Mar 3;13(3):467. doi: 10.3390/biom13030467

Reichinger D, Reithofer M, Hohagen M, Drinic M, Tobias J, Wiedermann U et al. A Biomimetic, Silaffin R5-Based Antigen Delivery Platform. Pharmaceutics. 2023 Jan;15(1):121. doi: 10.3390/pharmaceutics15010121

Dowman LJ, Kulkarni SS, Alegre-Requena J, Giltrap AM, Norman AR, Sharma A et al. Site-selective photocatalytic functionalization of peptides and proteins at selenocysteine. Nature Communications. 2022 Nov 12;13(1):6885. doi: 10.1038/s41467-022-34530-z

Hengxi Z, Modenutti C, Nekkanti YPK, Denis M, Bermejo IA, Lefèbre J et al. Identification of the Allosteric Binding Site for Thiazolopyrimidine on the C-Type Lectin Langerin. ACS Chemical Biology. 2022 Oct 21;17(10):2728–2733. Epub 2022 Sep 26. doi: 10.1021/acschembio.2c00626

Kerul L, Schrems M, Schmid A, Meli R, Becker CFW, Bello C. Semisynthesis of Homogeneous, Active Granulocyte Colony-Stimulating Factor Glycoforms. Angewandte Chemie (International Edition). 2022 Sep 26;61(39):1-10. e202206116. doi: 10.1002/anie.202206116

Epasto LM, Honegger P, Che K, Kozak F, Jörg F, Schröder C et al. Nuclear Overhauser spectroscopy in hyperpolarized water - chemical vs. magnetic exchange. Chemical Communications. 2022 Sep;58(83):11661-11664. doi: 10.1039/d2cc03735a

Kouhnavardi S, Ecevitoglu A, Dragacevic V, Sanna F, Arias-Sandoval E, Kalaba P et al. A Novel and Selective Dopamine Transporter Inhibitor, (S)-MK-26, Promotes Hippocampal Synaptic Plasticity and Restores Effort-Related Motivational Dysfunctions. Biomolecules. 2022 Jul;12(7):881. doi: 10.3390/biom12070881

Hering A, Jieu B, Jones A, Muttenthaler M. Approaches to Improve the Quantitation of Oxytocin in Human Serum by Mass Spectrometry. Frontiers in Chemistry. 2022 Jun 9;10:889154. doi: 10.3389/fchem.2022.889154

Negroni M, Guarin D, Che K, Epasto LM, Turhan E, Selimovic A et al. Inversion of Hyperpolarized 13C NMR Signals through Cross-Correlated Cross-Relaxation in Dissolution DNP Experiments. Journal of Physical Chemistry B. 2022 Jun 8;126(24):4599-4610. doi: 10.1021/acs.jpcb.2c03375

Kulkarni SS, Watson EE, Maxwell JWC, Niederacher G, Johansen-Leete J, Huhmann S et al. Expressed Protein Selenoester Ligation. Angewandte Chemie (International Edition). 2022 May 9;61(20):e202200163. doi: 10.1002/anie.202200163

Hilty C, Kurzbach D, Frydman L. Hyperpolarized water as universal sensitivity booster in biomolecular NMR. Nature Protocols. 2022 May;17(7):1621-1657. doi: 10.1038/s41596-022-00693-8

Kremsmayr T, Aljnabi A, Blanco-Canosa JB, Tran HNT, Emidio NB, Muttenthaler M. On the Utility of Chemical Strategies to Improve Peptide Gut Stability. Journal of Medicinal Chemistry. 2022 Apr 28;65(8):6191-6206. doi: 10.1021/acs.jmedchem.2c00094

Hanna C, Kriegesmann J, Dowman L, Becker C, Payne RJ. Chemical Synthesis and Semisynthesis of Lipidated Proteins. Angewandte Chemie (International Edition). 2022 Apr 4;61(15):e202111266. doi: 10.1002/anie.202111266

Klein K, Garkov D, Rütschlin S, Böttcher T, Schreiber F. QSDB—a graphical Quorum Sensing Database. Database: The Journal of Biological Databases and Curation. 2021 Nov 26;2021:baab058. doi: 10.1093/database/baab058

Böttcher T, Nguyen THN, Szamosvari D. Synthesis of bacterial 2-alkyl-4(1H)-quinolone derivatives. ARKIVOC. 2021 Nov 12;2021(9):218-239. doi: 10.24820/ark.5550190.p011.547

Muratspahic E, Retzl B, Dürrauer L, Freissmuth M, Becker CFW, Gruber CW. Genome Mining-Based Discovery of Blenny Fish-Derived Peptides Targeting the Mouse κ-Opioid Receptor. Frontiers in Pharmacology. 2021 Oct 22;12:773029. doi: 10.3389/fphar.2021.773029

Bialas F, Reichinger D, Becker CFW. Biomimetic and biopolymer-based enzyme encapsulation. Enzyme and microbial Technology. 2021 Oct;150:109864. doi: 10.1016/j.enzmictec.2021.109864

Baumgartner M, Lang M, Holley H, Crepaz D, Hausmann B, Pjevac P et al. Mucosal Biofilms Are an Endoscopic Feature of Irritable Bowel Syndrome and Ulcerative Colitis. Gastroenterology. 2021 Oct;161(4):1245-1256. Epub 2021 Jun 16. doi: 10.1053/j.gastro.2021.06.024

Epasto LM, Georges T, Selimovic A, Guigner J-M, Azais T, Kurzbach D. Formation and Evolution of Nanoscale Calcium Phosphate Precursors under Biomimetic Conditions. Analytical Chemistry. 2021 Jul 27;93(29):10204-10211. doi: 10.1021/acs.analchem.1c01561

Emidio NB, Meli R, Tran HNT, Baik H, Morisset-Lopez S, Elliott AG et al. Chemical Synthesis of TFF3 Reveals Novel Mechanistic Insights and a Gut-Stable Metabolite. Journal of Medicinal Chemistry. 2021 Jul 18;64(13):9484-9495. doi: 10.1021/acs.jmedchem.1c00767

Emidio NB, Tran HNT, Andersson A, Dawson PE, Albericio F, Vetter I et al. Improving the Gastrointestinal Stability of Linaclotide. Journal of Medicinal Chemistry. 2021 Jun 24;64(12):8384-8390. doi: 10.1021/acs.jmedchem.1c00380

Kress T, Che K, Epasto LM, Kozak F, Negroni M, Olsen GL et al. A novel sample handling system for dissolution dynamic nuclear polarization experiments. Magnetic Resonance. 2021 Jun 4;2(1):387–394. doi: 10.5194/mr-2-387-2021

Prothiwa M, Filz V, Oehler S, Boettcher T. Inhibiting quinolone biosynthesis of Burkholderia. Chemical Science. 2021 May 28;12(20):6908-6912. doi: 10.1039/d0sc06167k

Ray RM, Hansen AH, Taskova M, Jandl B, Hansen J, Soemardy C et al. Enhanced target cell specificity and uptake of lipid nanoparticles using RNA aptamers and peptides. Beilstein Journal of Organic Chemistry. 2021 Apr 26;17:891-907. doi: 10.3762/bjoc.17.75

Muttenthaler M, King GF, Adams DJ, Alewood PF. Trends in peptide drug discovery. Nature Reviews Drug Discovery. 2021 Apr 1;20(4):309-325. doi: 10.1038/s41573-020-00135-8

Showing entries 1 - 50 out of 150