Publications

Novakovic M, Olsen GL, Pinter G, Hymon D, Fuertig B, Schwalbe H et al. A 300-fold enhancement of imino nucleic acid resonances by hyperpolarized water provides a new window for probing RNA refolding by 1D and 2D NMR. Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2020 Feb 4;117(5):2449-2455. doi: 10.1073/pnas.1916956117

Groß K, Kurzbach D , Angele CM. NMR for food profiling – Long Drink, Short Experiment: Ein interdisziplinärer Zugang zur Förderung von Urteilskompetenz. Haushalt in Bildung und Forschung. 2020;9(4):79-96. doi: 10.3224/hibifo.v9i4.06

Muttenthaler M, Nevin ST, Inserra M, Lewis RJ, Adams DJ, Alewood PF. On-Resin Strategy to Label α-Conotoxins: Cy5-RgIA, a Potent α9α10 Nicotinic Acetylcholine Receptor Imaging Probe. Australian Journal of Chemistry. 2020;73(4):327-333. doi: 10.1071/CH19456

Conibear AC, Schmid A, Kamalov M, Becker CFW, Bello C. Recent Advances in Peptide-Based Approaches for Cancer Treatment. Current Medicinal Chemistry. 2020;27(8):1174-1205. doi: 10.2174/0929867325666171123204851

Dürrauer L, Muratspahic E, Gattringer J, Keov P, Mendel HC, Pfleger KDG et al. I8-arachnotocin-an arthropod- derived G protein-biased ligand of the human vasopressin V-2 receptor. Scientific Reports. 2019 Dec 17;9(1):19295. doi: 10.1038/s41598-019-55675-w

Jin AH, Muttenthaler M, Dutertre S, Himaya SWA, Kaas Q, Craik DJ et al. Conotoxins: Chemistry and Biology. Chemical Reviews. 2019 Nov 13;119(21):11510-11549. doi: 10.1021/acs.chemrev.9b00207

Conibear AC, Rosengren KJ, Becker CFW, Kaehlig H. Random coil shifts of posttranslationally modified amino acids. Journal of Biomolecular NMR. 2019 Nov;73(10-11):587-599. doi: 10.1007/s10858-019-00270-4

Hackl S, Becker CFW. Prion protein-Semisynthetic prion protein (PrP) variants with posttranslational modifications. Journal of Peptide Science. 2019 Oct;25(10):e3216. doi: 10.1002/psc.3216

Schlatzer T, Kriegesmann J, Schroeder H, Trobe M, Lembacher-Fadum C, Santner S et al. Labeling and Natural Post-Translational Modification of Peptides and Proteins via Chemoselective Pd-Catalyzed Prenylation of Cysteine. Journal of the American Chemical Society. 2019 Sept 18;141(37):14931-14937. doi: 10.1021/jacs.9b08279

Del Favero G, Bialas F, Grabher-Wusche S, Wittig A, Bräuer B, Gerthsen D et al. Silica particles with a quercetin-R5 peptide conjugate are taken up into HT-29 cells and translocate into the nucleus. Chemical Communications. 2019 Aug 21;55(65):9649-9652. doi: 10.1039/c9cc02215e

Sadet A, Stavarache C, Bacalum M, Radu M, Bodenhausen G, Kurzbach D et al. Hyperpolarized Water Enhances Two-Dimensional Proton NMR Correlations: A New Approach for Molecular Interactions. Journal of the American Chemical Society. 2019 Aug 14;141(32):12448-12452. doi: 10.1021/jacs.9b03651

Jannin S, Dumez JN, Giraudeau P, Kurzbach D. Application and methodology of dissolution dynamic nuclear polarization in physical, chemical and biological contexts. Journal of Magnetic Resonance. 2019 Aug;305:41-50. doi: 10.1016/j.jmr.2019.06.001

Kiryutin AS, Rodin BA, Yurkovskaya AV, Ivanov KL, Kurzbach D, Jannin S et al. Transport of hyperpolarized samples in dissolution-DNP experiments. Physical Chemistry Chemical Physics. 2019 Jul 7;21(25):13696-13705. doi: 10.1039/c9cp02600b

Sicoli G, Vezin H, Ledolter K, Kress T, Kurzbach D. Conformational tuning of a DNA-bound transcription factor. Nucleic Acids Research. 2019 Jun 4;47(10):5429-5435. doi: 10.1093/nar/gkz291

Poetgens AJG, Conibear AC, Altdorf C, Hilzendeger C, Becker CFW. Tumor-Targeting Immune System Engagers (ISErs) Activate Human Neutrophils after Binding to Cancer Cells. Biochemistry. 2019 Jun 4;58(22):2642-2652. doi: 10.1021/acs.biochem.9b00169

Kress T, Walrant A, Bodenhausen G, Kurzbach D. Long-Lived States in Hyperpolarized Deuterated Methyl Groups Reveal Weak Binding of Small Molecules to Proteins. Journal of Physical Chemistry Letters. 2019 Apr 4;10(7):1523-1529. doi: 10.1021/acs.jpclett.9b00149

Conibear AC, Thewes K, Groysbeck N, Becker CFW. Multifunctional Scaffolds for Assembling Cancer-Targeting Immune Stimulators Using Chemoselective Ligations. Frontiers in Chemistry. 2019 Mar 6;7:113. doi: 10.3389/fchem.2019.00113

Kamalov M, Kaehlig H, Rentenberger C, Müllner A, Peterlik H , Becker CFW. Ovalbumin Epitope SIINFEKL Self-Assembles into a Supramolecular Hydrogel. Scientific Reports. 2019 Feb 25;9(1):2696. doi: 10.1038/s41598-019-39148-8

Ellmer D, Brehs M, Haj-Yahya M, Lashuel HA, Becker CFW. Single Posttranslational Modifications in the Central Repeat Domains of Tau4 Impact its Aggregation and Tubulin Binding. Angewandte Chemie (International Edition). 2019 Feb 4;58(6):1616-1620. doi: 10.1002/anie.201805238

Conibear AC, Watson EE, Payne RJ, Becker CFW. Native chemical ligation in protein synthesis and semi-synthesis. Chemical Society Reviews. 2018 Dec 21;47(24):9046-9068. doi: 10.1039/c8cs00573g

Liutkeviciute Z, Gil-Mansilla E, Eder T, Casillas-Perez B, Di Giglio MG, Muratspahic E et al. Oxytocin-like signaling in ants influences metabolic gene expression and locomotor activity. The FASEB Journal. 2018 Dec;32(12):6808-6821. doi: 10.1096/fj.201800443

Kamalov M, Capel PD, Rentenberger C, Müllner A, Peterlik H , Becker CFW. Silaffin-Inspired Peptide Assemblies Template Silica Particles with Variable Morphologies. Chemnanomat. 2018 Dec;4(12):1209-1213. doi: 10.1002/cnma.201800340

Pfaff S, Nehring T, Pichler V, Cardinale J, Mitterhauser M, Hacker M et al. Development and evaluation of a rapid analysis for HEPES determination in ⁶⁸Ga-radiotracers. EJNMMI Research. 2018 Oct 23;8(1):95. doi: 10.1186/s13550-018-0449-6, 10.1186/s13550-018-0449-6

Herzig V, de Araujo AD, Greenwood KP, Chin YKY, Windley MJ, Chong Y et al. Evaluation of chemical strategies for improving the stability and oral toxicity of insecticidal peptides. Biomedicines. 2018 Sept 1;6(3):90. doi: 10.3390/biomedicines6030090

Feichtinger M, Sara T, Platzer G, Mateos B, Bokhovchuk F, Chène P et al. 1H, 13C, 15N resonance assignment of human YAP 50–171 fragment. Biomolecular NMR Assignments. 2018 Apr;12(1):179-182. doi: 10.1007/s12104-018-9805-8

Conibear AC, Poetgens AJG, Thewes K, Altdorf C, Hilzendeger C, Becker CFW. Synthetic Cancer-Targeting Innate Immune Stimulators Give Insights into Avidity Effects. ChemBioChem: a european journal of chemical biology. 2018 Mar 2;19(5):459-469. doi: 10.1002/cbic.201700522

Hufnagel B, Silberbauer K, Löppert R, Viernstein H, Praznik W, Müller M. Fermentation of non-digestible raffinose family oligosaccharides and galactomannans by probiotics. Trends in Food Science & Technology. 2018 Mar;9(3):1638-1646. doi: 10.1039/c7fo01887h

Kamalov M, Hajradini A, Rentenberger C , Becker CFW. N-terminal residues of silaffin peptides impact morphology of biomimetic silica particles. Materials Letters. 2018 Feb 1;212:114-117. doi: 10.1016/j.matlet.2017.10.050

Arrowsmith S, Keov P, Muttenthaler M, Gruber CW. Contractility Measurements of Human Uterine Smooth Muscle to Aid Drug Development. Journal of Visualized Experiments. 2018 Jan;2018(131):e56639. doi: 10.3791/56639

Matveenko M, Hackl S, Becker CFW. Utility of the Phenacyl Protecting Group in Traceless Protein Semisynthesis through Ligation-Desulfurization Chemistry. ChemistryOpen. 2018 Jan;7(1):106-110. doi: 10.1002/open.201700180

Brehs M, Poetgens AJG, Steitz J, Thewes K, Schwarz J, Conibear AC et al. Synthetic integrin-binding immune stimulators target cancer cells and prevent tumor formation. Scientific Reports. 2017 Dec 14;7:17592. doi: 10.1038/s41598-017-17627-0

Muttenthaler M, Andersson A, Vetter I, Menon R, Busnelli M, Ragnarsson L et al. Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species. Science Signaling. 2017 Dec 5;10(508):eaan3398. doi: 10.1126/scisignal.aan3398

Gell AL, Groysbeck N, Becker CFW, Conibear AC. A comparative study of synthetic and semisynthetic approaches for ligating the epidermal growth factor to a bivalent scaffold. Journal of Peptide Science. 2017 Dec;23(12):871-879. doi: 10.1002/psc.3051

Hellinger R, Thell K, Vasileva M, Muhammad T, Gunasekera S, Kuemmel D et al. Chemical Proteomics for Target Discovery of Head-to-Tail Cyclized Mini-Proteins. Frontiers in Chemistry. 2017 Oct 11;5:73. doi: 10.3389/fchem.2017.00073

Pasalic D, Weber B, Giannone C, Anelli T, Mller R, Fagioli C et al. A peptide extension dictates IgM assembly. Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2017 Oct 10;114(41):E8575-E8584. doi: 10.1073/pnas.1701797114

Conibear AC, Hager S, Mayr J, Klose MHM, Keppler BK , Kowol CR et al. Multifunctional α _vβ ₆ Integrin-Specific Peptide-Pt(IV) Conjugates for Cancer Cell Targeting. Bioconjugate Chemistry. 2017 Sept 20;28(9):2429-2439. doi: 10.1021/acs.bioconjchem.7b00421

Bello C, Becker CFW. A dual functional peptide-auxiliary conjugate for C-to-N and N-to-C sequential native chemical ligation of glycopeptides. Bioorganic & Medicinal Chemistry. 2017 Sept 15;25(18):5016-5021. doi: 10.1016/j.bmc.2017.05.046

Matveenko M, Becker CFW. Synthetic Approach to Argpyrimidine as a Tool for Investigating Nonenzymatic Posttranslational Modification of Proteins. Synlett: accounts and rapid communications in synthetic organic chemistry. 2017 Sept;28(15):1950-1955. doi: 10.1055/s-0036-1588225

Araman C, Thompson RE, Wang S, Hackl S, Payne RJ, Becker CFW. Semisynthetic prion protein (PrP) variants carrying glycan mimics at position 181 and 197 do not form fibrils. Chemical Science. 2017 Jul 24;8(9):6626-6632. doi: 10.1039/c7sc02719b

Kaur H, Kamalov M, Brimble MA. Chemical Synthesis of Peptides Containing Site-Specific Advanced Glycation Endproducts. Accounts of Chemical Research. 2016 Oct 18;49(10):2199-2208. doi: 10.1021/acs.accounts.6b00366

Schwaighofer A, Alcaraz MR, Araman MC, Goicoechea H, Lendl B. External cavity-quantum cascade laser infrared spectroscopy for secondary structure analysis of proteins at low concentrations. Scientific Reports. 2016 Sept 16;6:33556. doi: 10.1038/srep33556

Matveenko M, Cichero E, Fossa P, Becker CFW. Impaired Chaperone Activity of Human Heat Shock Protein Hsp27 Site-Specifically Modified with Argpyrimidine. Angewandte Chemie (International Edition). 2016 Sept 12;55(38):11397-11402. doi: 10.1002/anie.201605366

Aladini F, Araman MC, Becker CFW. Chemical synthesis and characterization of elastin-like polypeptides (ELPs) with variable guest residues. Journal of Peptide Science. 2016 May;22(5):334-342. doi: 10.1002/psc.2871

Koehbach J, Gruber CW, Becker C, Kreil DP, Jilek A. MALDI TOF/TOF-Based Approach for the Identification of D- Amino Acids in Biologically Active Peptides and Proteins. Journal of Proteome Research. 2016 May;15(5):1487-1496. doi: 10.1021/acs.jproteome.5b01067

Martelli T, Ravera E, Louka A, Cerofolini L, Hafner M, Fragai M et al. Atomic-Level Quality Assessment of Enzymes Encapsulated in Bioinspired Silica. Chemistry: A European Journal. 2016 Jan 4;22(1):425-432. doi: 10.1002/chem.201503613

Conibear AC, Chaousis S, Durek T, Rosengren KJ, Craik DJ, Schroeder CI. Approaches to the Stabilization of Bioactive Epitopes by Grafting and Peptide Cyclization. Biopolymers: original research on biological molecules and assemblies. 2016 Jan;106(1):89-100. doi: 10.1002/bip.22767

Conibear AC, Farbiarz K, Mayer RL, Matveenko M, Kählig H, Becker CFW. Arginine side-chain modification that occurs during copper-catalysed azide-alkyne click reactions resembles an advanced glycation end product. Organic & Biomolecular Chemistry. 2016;14(26):6205-6211. doi: 10.1039/c6ob00932h

Lechner CC, Becker CFW. Silaffins in Silica Biomineralization and Biomimetic Silica Precipitation. Marine Drugs. 2015 Aug;13(8):5297-5333. doi: 10.3390/md13085297

Bello C, Wang S, Meng L, Moremen KW, Becker CFW. A PEGylated Photocleavable Auxiliary Mediates the Sequential Enzymatic Glycosylation and Native Chemical Ligation of Peptides. Angewandte Chemie (International Edition). 2015 Jun 22;54(26):7711-7715. doi: 10.1002/anie.201501517

Bello C, Kikul F, Becker CFW. Efficient generation of peptide hydrazides via direct hydrazinolysis of Peptidyl-Wang-TentaGel resins. Journal of Peptide Science. 2015 Mar;21(3):201-207. doi: 10.1002/psc.2747

Publications Institut of Biological Chemistry (founded 2011)